Method Development and Validation of Mebeverine HCl in Bulk Drugs by Using Spectrophotometric Method

Parag. S. Mahadik; Senthilkumar. G. P

doi:10.5958/0974-360X.2016.00272.9

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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Method Development and Validation of Mebeverine HCl in Bulk Drugs by Using Spectrophotometric Method

Author(s): Parag. S. Mahadik, Senthilkumar. G. P

Email(s): drsenn78@gmail.com

DOI: 10.5958/0974-360X.2016.00272.9

Address: Parag. S. Mahadik1,2, Senthilkumar. G. P1*
1Bharathi College of Pharmacy, Bharathinagara.
2Pacific Academy of Higher Education and Research, Udaipur.
*Corresponding Author

Published In: Volume - 9, Issue - 9, Year - 2016

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ABSTRACT:
In the present research a simple, accurate, precise and cost effective UV-Vis spectrophotometric method for the estimation of Mebeverine HCl in bulk was illustrated. The absorption maxima of the drug was found to be 220 nm in 0.1 N HCl. A linear response was observed in the range of 5-15 µg/ml with a regression coefficient of 1.0. Validation parameters were carried out as per the guidelines of International Conference for Harmonization. This method can be used in the industries for determination of Mebeverine HCl to analyze the quality of Mebeverine HCl without any interference.

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Cite this article:
Parag. S. Mahadik, Senthilkumar. G. P. Method Development and Validation of Mebeverine HCl in Bulk Drugs by Using Spectrophotometric Method. Research J. Pharm. and Tech 2016; 9(9):1407-1409. doi: 10.5958/0974-360X.2016.00272.9

Cite(Electronic):
Parag. S. Mahadik, Senthilkumar. G. P. Method Development and Validation of Mebeverine HCl in Bulk Drugs by Using Spectrophotometric Method. Research J. Pharm. and Tech 2016; 9(9):1407-1409. doi: 10.5958/0974-360X.2016.00272.9 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2016-9-9-24