Author(s):
Chandan Yadav, Md. Asif, Juber Akhtar, Badruddeen, Mohammad Irfan Khan, Saquib, Tanweer, Mohammad Ahmad, Laiba Rind
Email(s):
juberakhtar@gmail.com
DOI:
10.5958/0974-360X.2020.01092.6 
Address:
Chandan Yadav, Md. Asif, Juber Akhtar*, Badruddeen, Mohammad Irfan Khan, Saquib, Tanweer, Mohammad Ahmad, Laiba Rind
Department of Pharmacy, Integral University, Kursi Road, Lucknow (U.P.) - 226026.
*Corresponding Author
Published In:
Volume - 13,
Issue - 12,
Year - 2020
ABSTRACT:
Curcumin (Cur) is broadly accepted for its useful functions. Cur has low water solubility therefore its application in drug delivery became a challenge for researchers. To overcome the absorption, bioavailability and overall biochemical/structural degradation we may develop pro-liposomes and liposomes of Cur. The pro-liposomes generally administrated by orally, topically and parentally and mainly used in cosmetic and hair technologies, diagnostic purpose, sustained release formulations and as good carriers in gene delivery. This review highlights the speculative approach and some new advancement for the preparation of pro-liposomes in general. Various methods to formulate pro-liposomes (Film-deposition carrier method, Spray drying method, Fluidized-bed method, Supercritical anti-solvent method), evaluation parameters (Hydration study, Zeta potential, Flow property) thereof and applications of pro-liposome are highlighted. This may help for further preparation and evaluation of Cur. based formulations. Additionally different features of curcumin related to its pharmacological profile and mechanism of protection in various ailments have been reported.
Cite this article:
Chandan Yadav, Md. Asif, Juber Akhtar, Badruddeen, Mohammad Irfan Khan, Saquib, Tanweer, Mohammad Ahmad, Laiba Rind. An outline on Curcumin: Its pro-liposome and Liposome Formulations. Research J. Pharm. and Tech. 2020; 13(12):6276-6283. doi: 10.5958/0974-360X.2020.01092.6
Cite(Electronic):
Chandan Yadav, Md. Asif, Juber Akhtar, Badruddeen, Mohammad Irfan Khan, Saquib, Tanweer, Mohammad Ahmad, Laiba Rind. An outline on Curcumin: Its pro-liposome and Liposome Formulations. Research J. Pharm. and Tech. 2020; 13(12):6276-6283. doi: 10.5958/0974-360X.2020.01092.6 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2020-13-12-107
REFERENCES:
1. Borrin TR, Georges EL, Moraes ICF, Pinho SC. Curcumin-loaded nanoemulsions produced by the emulsion inversion point (EIP) method: An evaluation of process parameters and physico-chemical stability. Journal of Food Engineering. 2016; 169: 1–9.
2. Liu Y, Ying D, Cai Y, Le X. Improved antioxidant activity and physicochemical properties of curcumin by adding ovalbumin and its structural characterization.FoodHydrocolloids.2017;72:304-311
3. Aditya N.P, Shim M, Lee I., Lee Y, Im M H, Ko S. Curcumin and genistein coloaded nanostructured lipid carriers: In vitro digestion and antiprostate cancer activity. Journal of Agricultural and Food Chemistry.2013; 61:1878–1883
4. Chaves M.A, Oseliero-Filho P. L, Jange C.G, Sinigaglia-Coimbra R, Oliveira C. L P. Pinho, S. C. Structural characterization of multilamellar liposomes coencapsulating curcumin and vitamin D3. Colloids and Surfaces A: Physicochemical and Engineering Aspects.2018;549:112-121
5. Taylor T. M, Davidson P. M, Bruce B.D, Weiss J. Liposomal nanocapsules in food science and agriculture. Critical Reviews in Food Science and Nutrition.2005;45:587–605.
6. Laye C, McClements D. J, Weiss J. Formation of biopolymer-coated liposomes by electrostatic deposition of chitosan. Journal of Food Science.2008 ;73: N7–N15
7. Wagner A, Vorauer-Uhl K. Liposome technology for industrial purposes. Journal of Drug Delivery.2011, 1–9.
8. Rojanarat W, Changsan N, Tawithong E, Pinsuwan S, Chan HK, et al. Isoniazid proliposome powders for inhalation—preparation, characterization and cell culture studies. Intern J Mol Sci.2011; 12: 4414-4434.
9. Silva G. S, Jange C. G, Rocha J. S. S, Chaves M. A, Pinho S. C. Characterisation of curcumin-loaded proliposomes produced by coating of micronized sucrose and hydration of phospholipid powders to obtain multilamellar liposomes. International Journal of Food Science Technology. 2017; 52:772–780
10. Janga KY, Jukanti R, Velpula A, Sunkavalli S, Bandari S, et al. 2012; Bioavailability enhancement of zaleplon via proliposomes: Role of surface charge. Euro J Phar Biop 80: 347-357.
11. Miłobȩdzka J, van Kostanecki S, Lampe V 1910; "Zur Kenntnis des Curcumins". Berichte der Deutschen Chemischen Gesellschaft. 43 (2): 2163- 2170. "EPA Method 212.3: Boron (Colorimetric, Curcumin)" (PDF).
12. Silva G. S, Jange C. G, Rocha J. S. S, Chaves M. A, Pinho S. C. 2017;Characterisation of curcumin-loaded proliposomes produced by coating of micronized sucrose and hydration of phospholipid powders to obtain multilamellar liposomes. International Journal of Food Science & Technology, 52:772–780.
13. Song KH, Chung SJ, Shim CK (2002) Preparation and evaluation of proliposomes containing salmon calcitonin. J Con Rel 84: 27-37.
14. Janga KY, Jukanti R, Velpula A, Sunkavalli S, Bandari S, et al. 2012; Bioavailability enhancement of zaleplon via proliposomes: Role of surface charge. Euro J Phar Biop 80: 347-357.
15. Rojanarat W, Changsan N, Tawithong E, Pinsuwan S, Chan HK, et al. 2011;Isoniazid proliposome powders for inhalation—preparation, characterization and cell culture studies. Intern J Mol Sci 12: 4414-4434.
16. Xu H, He L, Nie S, Guan J, Zhang X, et al. 2009; Optimized preparation of vinpocetine proliposomes by a novel method and in vivo evaluation of its pharmacokinetics in New Zealand rabbits. J Con Rel 140: 61-68.
17. Lo YL, Tsai JC, Kuo JH 2004; Liposomes and disaccharides as carriers in spray-dried powder formulations of superoxide dismutase. J Con Rel 94: 259-272.
18. Alves GP, Santana MHA 2004; Phospholipid dry powders produced by spray drying processing: structural, thermodynamic and physical properties. Pow Tech 145: 139-148
19. Colonna C, Conti B, Genta I, Alpar OH 2008; Non-viral dried powders for respiratory gene delivery prepared by cationic and chitosan loaded liposomes. Inter J Phar 364: 108-118.
20. Vyas SP, Khar RK 2002; Submicron emulsions in targeted and controlled drug delivery. Novel Carrier Systems.
21. Yan-Yu X, Yun Mei S, Zhi-Peng C, Qi-Neng P 2006; Preparation of silymarin proliposome: a new way to increase oral bioavailability of silymarin in beagle dogs. Inter Phar 319: 162-168.
22. Payne NI, Browning I, Hynes CA 1986; Characterization of proliposomes. J Phar Sciences 75: 330-333.
23. Martin A 1993; Physical pharmacy: physical chemical principles in the pharmaceutical sciences: BI Waverly Pvt. Ltd.
24. Burgess DJ, 2005; Injectable dispersed systems: Formulation, processing, and performance. Boca Raton: Taylor & Francis Vemuri S, Rhodes C 1995; Preparation and characterization of liposomes as therapeutic delivery systems: a review. Pharm Ac Hel 70: 95-111.
25. Song KH, Chung SJ, Shim CK 2002; Preparation and evaluation of pro-liposomes containing salmon calcitonin. J Con Rel 84: 27-37.
26. Hwang BY, Jung BH, Chung SJ, Lee MH, Shim CK 1997; In vitro skin permeation of nicotine from pro-liposomes. Journal of Controlled Release 49: 177-184.
27. Bari H 2010; A prolonged release parenteral drug delivery system-an overview. Int J Pharm Sci Rev Res 3: 1-11.
28. Kumar R, Gupta RB, Betegeri G 2001; Formulation, characterization, and in vitro release of glyburide from pro-liposomal beads. Drug Delivery 8: 25-27.
29. Nalla P, Bagam S, Eedara BB, Dhurke R 2015; Formulation and Evaluation of Domperidone Oral Proliposomal Powders. International Journal of Pharmatech Research 7: 108-118.
30. Song KH, Chung SJ, Shim CK 2002; Preparation and evaluation of proliposomes containing salmon calcitonin. J Con Rel 84: 27-37.
31. Brocks DR, Betageri GV 2002; Enhanced oral absorption of halofantrine enantiomers after encapsulation in a proliposomal formulation. Journal of Pharmacy and Pharmacology 54: 1049-1053.
32. Chen Y, Lu Y, Chen J, Lai J, Sun J, et al. 2009; Enhanced bioavailability of the poorly water-soluble drug fenofibrate by using liposomes containing a bile salt. International Journal of Pharmaceutics 376: 153-160.
33. Taylor KM, Elhissi AM 2006; Preparation of liposomes for pulmonary delivery using medical nebulizers. Liposome Technology Liposome Preparation and Related Techniques 1: 67-84
34. Chougule M, Padhi B, Misra A 2008; Development of spray dried liposomal dry powder inhaler of dapsone. Aaps Pharmscitech 9: 47-53.
35. Sweeney LG, Wang Z, Loebenberg R, Wong JP, Lange CF, et al. 2005; Spray freeze dried liposomal ciprofloxacin powder for inhaled aerosol drug delivery. International Journal of Pharmaceutics 305: 180-185.
36. Arora P, Sharma S, Garg S 2002; Permeability issues in nasal drug delivery. Drug Discovery Today 7: 967-975.
37. Jukanti R, Sheela S, Bandari S, Veerareddy PR 2011; Enhanced bioavailability of exemestane via proliposomes based transdermal delivery. Journal of Pharmaceutical Sciences 100: 3208-3222.
38. Hiremath R, Gowda D, Raj A, Shamant BS, SrivastavaA, et al. 2016; Pro-liposomes: A novel approach to carrier drug delivery system. Journal of Chemical and Pharmaceutical Research 8: 348-354.