Author(s):
Prevesh Kumar, Md. Rageeb Md. Usman, Aditya Sharma, Diskha, Munesh Mani, Pawan Singh, Navneet Verma
Email(s):
kpravesh92@gmail.com
DOI:
10.5958/0974-360X.2020.00521.1
Address:
Prevesh Kumar1*, Md. Rageeb Md. Usman2, Aditya Sharma1, Diskha1, Munesh Mani1, Pawan Singh1, Navneet Verma1
1Faculty of Pharmacy, IFTM University, Lodhipur Rajput, Moradabad, U. P., India.
2Department of Pharmacognosy, Smt. S. S. Patil College of Pharmacy, Chopda, India.
*Corresponding Author
Published In:
Volume - 13,
Issue - 6,
Year - 2020
ABSTRACT:
Recently pharmaceutical preparations used for elderly patients have been investigated to improve the treatment compliances and quality of life of patients. Recent advances in Novel Drug Delivery System (NDDS) aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for administration and to achieve better patient compliance. One such approach is "Mouth Dissolving Tablet" are disintegrates instantaneously when placed on tongue, releasing the drug that dissolves or disperses in the saliva. Mouth Dissolving Drug Delivery System emerged from the desire to provide patient with conventional mean of taking their medication. Difficulty in swallowing (Dysphagia) is a common problem of all age groups, especially elderly and pediatrics, because of physiological changes associated with these groups of patients. The saliva containing the dissolved or dispersed medicament is then swallowed and the drug is absorbed in the normal way. Some drugs are absorbed from the mouth, pharynx and esophagus as the saliva passes down into the stomach & it may produce rapid onset of action. Bioavailability of drug is significantly greater than those observed from conventional tablet dosage form.
Cite this article:
Prevesh Kumar, Md. Rageeb Md. Usman, Aditya Sharma, Diskha, Munesh Mani, Pawan Singh, Navneet Verma. Mouth Dissolving Tablets: A Modern Approach to Delivery of Drug. Research J. Pharm. and Tech 2020; 13(6): 2943-2950. doi: 10.5958/0974-360X.2020.00521.1
Cite(Electronic):
Prevesh Kumar, Md. Rageeb Md. Usman, Aditya Sharma, Diskha, Munesh Mani, Pawan Singh, Navneet Verma. Mouth Dissolving Tablets: A Modern Approach to Delivery of Drug. Research J. Pharm. and Tech 2020; 13(6): 2943-2950. doi: 10.5958/0974-360X.2020.00521.1 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2020-13-6-74
REFERENCES:
1. Seager HJ. Drug delivery products and zydis fast dissolving dosage forms. Pharm Pharmcol 1998; 50:375‐382.
2. Gohel M, Patel M, Amin A, Agrawal R, Dave R and Bariya N. Formulation design and optimization of mouth dissolve tablets of nimesulide using vacuum drying technique. AAPS Pharm Sci Tech 2004; 5:36.
3. Bhowmik Debjit ,Chiranjib, jaiswal Jyoti, Dubey Vinod, Chandira Margret A review on revolution of novel drug delivery system and new marketopportunitiesScholars Research Library 2009, 1 (2) 262-276.
4. Indurwade NH, Rajyaguru TH and Nakhat PD. Novel approach: Fast dissolving tablets. Indian Drugs 2002; 39(8): 405‐41.
5. Shukla D, Chakraborty S, Singh S, Mishra B. Mouth Dissolving Tablets I: An Overview of Formulation Technology, Sci Pharm. 2009; 77: 309–26.
6. Bhowmik Debjit, B. Chiranjib, Kant Krishna, Pankaj, R. Margret Chandira: Fast Dissolving Tablet: An Overview. Journal of Chemical and Pharmaceutical Research, 2009, 1(1): 163-177
7. Sunita Kumari, Visht Sharad, Sharma Pramod Kumar, Yadav Rakesh Kumar, Fast dissolving Drug delivery system: Review Article. Journal of Pharmacy Research 2010, 3(6), 1444-1449
8. Sahoo Susijit, Mishra B., Biswal P.K., Panda Omprakash, Mahapatra Santosh Kumar, Jana Goutam Kumar: Fast Dissolving Tablet: As A Potential Drug Delivery System. Drug Invention Today 2010,2(2),130-133
9. Wilson CG, Washington N, Peach J, Murray GR, Kennerley J. The behavior of a fast dissolving dosage form (Expidet) followed by g-scintigraphy. Int J Pharm. 1987; 40: 119–23.
10. Fix JA. Advances in quick-dissolving tablets technology employing Wowtab. Paper Presented at: IIR Conference on Drug Delivery Systems. 1998 Oct.; Washington DC, USA.
11. Virely P, Yarwood R. Zydis – a novel, Fast dissolving dosage form. Manuf Chem. 1990; 61: 36–37.
12. Jaccard TT, Leyder J. Une nouvelle forme galenique: le lyoc. [A new galenic form: lyoc]. Ann Pharm Fr. 1985; 43: 123–31.
13. Kuno Y, Kojima M, Ando S, Nakagami H. Evaluation of rapidly disintegrating tablets manufactured by phase transition of sugar alcohols. Journal of Controlled Release 2005; 105(1, suppl 2): 16-22.
14. Myers GL, Battist GE, Fuisz RC. Process and apparatus for making rapidly dissolving dosage units and product there from. PCT Patent WO 95/34293-A1; 1995.
15. Cherukuri SR, Myers GL, Battist GE, Fuisz RC. Quickly dispersing comestible unit and product. PCT Patent WO 95/34290-A1; 1995.
16. Cherukuri SR, Myers GL, Battist GE, Fuisz RC. Process for forming quickly dispersing comestible unit and product there from. US Patent 5587172; 1996.
17. Fuisz R. Ulcer prevention method using a melt-spun hydrogel. US Patent 5622717; 1997.
18. Abdelbary G, Prinderre P, Eouani C, Joachim J, Reynier J P, Piccerelle P. The preparation of orally disintegrating tablets using a hydrophilic waxy binder. International Journal of Pharmaceutics 2004; 278(2): 423-33.
19. Kuchekar, B. S., Mahajan, S., and Bandhan, A. C., Mouth dissolve tablets of sumatriptan, Indian Drugs, 2004, 41(10), 592-598.
20. Lalla. J K., Mamania, H. M., 2004, Fast dissolving rofecoxib tablets, Indian J. Pharm. Sci.,59(4), 23-26.
21. Dali Shukla, Subhashis Chakraborty, Sanjay singh, Brahemeshwar mishra. Mouth dissolving tablet I: An overview of formulation technology. Scientica Pharmaceutica. 2009; 77: 309-26.
22. Jaysukh J Hirani, Dhaval A Rathod, Kantilal R Vadalia. Orally disintegrating tablets: A Review. Tropical Journal of Pharmaceutical Research. 2009; 8(2): 161-72.
23. Schimidt P C, and Brogramann B., Pharmaceutical Technology. 1988 (34), 22.
24. Cohen Y, and Lach J L, Journal of Pharmaceutical Sciences. 1963(52), 122
25. US 8067033 (Nov 29, 2011) Stable compositions of famotidine.
26. U.S. patent 8067033: Stable compositions of famotidine and ibuprofen
27. Jain Shashank,A views Fast Dissolving Tablets. on Apr 06, 2009: 2,106(http://www.slideshare.net).
28. Cherukuri SR, Myers GL, Battist GE, Fuisz RC. Process for forming quickly dispersing comestible unit and product there from. US Patent 5587172; 1996.
29. Fuisz R, Cherukuri SR. Process and apparatus for making tablets and tablets made there from. US Patent 5654003; 1997.
30. Myers GL, Battist GE, Fuisz RC. Delivery of controlled-release systems. US Patent 5567439; 1996.
31. Cherukuri SR, Fuisz R. Process and apparatus for making tablets and tablets made there from. US Patent 5654003; 1997.
32. Myers GL, Battist GE, Fuisz RC. Ulcer prevention method using a melt-spun hydrogel. US Patent 5622719; 1997.