Author(s):
Kavitha K, Mohan.S, Srinivasan.N, Suresh. R
Email(s):
kavithakrocks@gmail.com
DOI:
10.5958/0974-360X.2021.00085.8 
Address:
Kavitha K1*, Mohan.S1, Srinivasan.N2, Suresh. R2
1Department of Pharmaceutical Chemistry, Karpagam College of Pharmacy, Ottakalpandapam, Coimbatore, Tamil Nadu.
2Department of Pharmacy, Faculty of Engineering and Technology, Annamalai University, Annamalai Nagar, Tamil Nadu.
*Corresponding Author
Published In:
Volume - 14,
Issue - 1,
Year - 2021
ABSTRACT:
Some novel Schiff bases of quinazolin-4-(3H)-one were synthesized in good yields and evaluated for their possible anti-bacterial, anti-fungal activities. The structures of the newly synthesized compounds were confirmed by their spectrum of IR, NMR, and MASS. Their antibacterial, fungal activities were evaluated by Plate hole diffusion method against gram positive, gram negative bacteria and Aspergillus Niger, candida albicans were used. The newly synthesized compounds showed moderate to significant anti-bacterial and fungal activities when compared to standard drug. The obtained results showed that the most active compounds could be useful as a template for future design and modification, investigation to produce more active pharmacophores.
Cite this article:
Kavitha K, Mohan.S, Srinivasan.N, Suresh. R. Design, Synthesis, Characterization of Antimicrobial activity of Schiff bases of novel Quinazolin-4-one Derivatives. Research J. Pharm. and Tech. 2021; 14(1):466-470. doi: 10.5958/0974-360X.2021.00085.8
Cite(Electronic):
Kavitha K, Mohan.S, Srinivasan.N, Suresh. R. Design, Synthesis, Characterization of Antimicrobial activity of Schiff bases of novel Quinazolin-4-one Derivatives. Research J. Pharm. and Tech. 2021; 14(1):466-470. doi: 10.5958/0974-360X.2021.00085.8 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-1-85
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