Author(s):
Vignesh. R, V. M. Padmapriya, Rajasekar. G
Email(s):
drvigneshpedo@gmail.com , padmanie2019@gmail.com , dr.rajasekar.gunasekaran@gmail.com
DOI:
10.5958/0974-360X.2021.00088.3
Address:
Dr. Vignesh. R1, Dr. V. M. Padmapriya2, Dr. Rajasekar. G3
1Senior Lecturer, Department of Pediatric and Preventive Dentistry, Saveetha Dental College and Hospitals, Saveetha University, Saveetha Institute of Medical and Technical Sciences, Velappanchavadi, Chennai – 77.
2Scientist - ‘B’, National Institute of Epidemiology, Indian Council of Medical Research, Department of Health Research, Ministry of Health and Family Welfare, Ayapakkam, Chennai – 77.
3Senior Lecturer, Department of Pediatric and Preventive Dentistry, Meenakshi Ammal Dental College and Hospitals, Meenakshi University, Alapakkam Main Road, Chennai – 95.
*Corresponding Author
Published In:
Volume - 14,
Issue - 1,
Year - 2021
ABSTRACT:
Aim: To summarize the basic and current concepts of algesia that is present in the day-to-day dental practice by a thorough systematic literature research of databases. Background: Electronic databases were used to conduct a computerized search like MEDLINE, PubMed, Scopus and Evidence-based Medicine reviews using the terms were “odontogenic pain”, “dental pain physiology”, “pain biology” and “chemical mediators in dental pain”. Review: The complexity of understanding pain transmission and its perception is of theoretical necessity for dental practitioners. The neurological aspects of pain, i.e. the innervation, stimulation of pain, conductance of pain and its mediators, are the basis that provides knowledge to the practitioners to provide effective pain management in their dental practice. Conclusion: Thorough knowledge about the neurobiology of pain is necessary to understand the pain perceived by the patients and thereby allows the practitioner to follow specific protocols of pain management.
Cite this article:
Vignesh. R, V. M. Padmapriya, Rajasekar. G. Dentalgesian Physiology: A Review on the Neurophysiology of pain in Dentistry. Research J. Pharm. and Tech. 2021; 14(1):482-486. doi: 10.5958/0974-360X.2021.00088.3
Cite(Electronic):
Vignesh. R, V. M. Padmapriya, Rajasekar. G. Dentalgesian Physiology: A Review on the Neurophysiology of pain in Dentistry. Research J. Pharm. and Tech. 2021; 14(1):482-486. doi: 10.5958/0974-360X.2021.00088.3 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-1-88
REFERENCES:
1. Clifford J. Woolf. Pain: Moving from Symptom Control toward Mechanism-Specific Pharmacologic Management. Ann Intern Med.2004;140(6):441-451.
2. Massieh Moayedi, Karen D. Davis. Theories of pain: from specificity to gate control. J Neurophysiol. 2013;109(1):5–12.
3. Vignesh. R, Vishnu Rekha C, Parisa Norouzi Baghkomeh, Sankar Annamalai, D. Ditto Sharmin. Algesia and Analgesia in Pediatric Dentistry. Research J. Pharm. and Tech. 2019; 12(5):2559-2565.
4. Goranka Prpić-Mehičić and Nada Galić. Odontogenic pain. Medical Sciences 2010; 34:43-54.
5. Ofelia L. Elvir-Lazo, Paul F. White. The role of multimodal analgesia in pain management after ambulatory surgery. Curr Opin Anesthesiol. 2010 23(6):697–703.
6. Natalia E. Morone, Debra K. Weiner. Pain as the 5th vital sign: Exposing the vital need for pain education. Clin Ther. 2013;35(11):1728–1732.
7. Henry MA, Hargreaves KM. Peripheral mechanisms of odontogenic pain. Dent Clin North Am. 2007 Jan;51(1):19–44.
8. Coutaux A, Adam F, Willer J-C, Le Bars D. Hyperalgesia and allodynia: peripheral mechanisms. Joint Bone Spine. 2005;72(5):359-71
9. Hucho T, Levine JD. Signaling Pathways in Sensitization: Toward a Nociceptor Cell Biology. Neuron. 2007;55(3):365-76.
10. Sacerdote P, Levrini L. Peripheral mechanisms of dental pain: the role of substance P. Mediators Inflamm. Article ID 951920, 6 pages, 2012. https://doi.org/10.1155/2012/951920.
11. Arthur C. Guyton, John E. Hall. Textbook of Medical Physiology. Eleventh Edition. Elsevier Inc.; 2006: pg. no. 598-609.
12. Kim Barrett, Heddwen Brooks, Scott Boitano, Susan Barman. Ganong’s review of Medical Physiology. Twenty-third Edition; McGraw-Hill Companies, Inc.; 2010: pg. no. 167-171.
13. Jeffery P. Okeson. Bell’s Orofacial Pain. Fifth edition. Quintessence Publishing Co Inc.; 1995: pg. no. 100-110.
14. E.S. Troullos, R.D. Freeman, R.A. Dionne. The Scientific Basis for Analgesic Use in Dentistry. Anesth Prog. 1986;33(3):123–138.
15. Ashley PF, Parekh S, Moles DR, Anand P, Behbehani A. Preoperative analgesics for additional pain relief in children and adolescents having dental treatment. Cochrane Database Syst Rev.2012;9. Art. No.: CD008392. doi: 10.1002/14651858.CD008392.pub2.
16. National Pharmaceutical Council. Pain: Current understanding of assessment management and treatments. www.americanpainsociety. org/uploads/pdfs/npc/section_1.pdf. (seen on 12.10.2014)
17. Jonathan Brooks, Irene Tracey. From nociception to pain perception: imaging the spinal and supraspinal pathways. J. Anat. 2005;207(1):19–33.
18. Hans-Georg Schaible, Andrea Ebersberger, Gabriel Natura. Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines. Arthritis Res Ther. 2011;13(2):210.
19. Min Lin, Zheng Yuan Luo, Bo Feng Bai, Feng Xu, Tian Jian Lu. Fluid Mechanics in Dentinal Microtubules Provides Mechanistic Insights into the Difference between Hot and Cold Dental Pain. PLoS ONE. 2011;6(3):e1806-8.
20. Niharika Jain, Abhishek Gupta, Meena N. An Insight Into Neurophysiology of Pulpal Pain: Facts and Hypotheses. Korean J Pain. 2013;26(4):347-355.
21. Paola Sacerdote, Luca Levrini. Peripheral Mechanisms of Dental Pain: The Role of Substance P. Mediators Inflamm. 2012, Article ID 951920.
22. G. S. Kumar. Orban's Oral Histology and Embryology. Thirteenth Edition. Elsevier Inc.; 2011: pg. no. 120-129.
23. Antonio Nanci. Ten Cate’s oral histology: development, structure and function. Eighth Edition. Elsevier publications; 2012: pg. no. 198-201.
24. Adrienne E. Dubin, Ardem Patapoutian. Nociceptors: the sensors of the pain pathway. J Clin Invest. 2010;120(11):3760-3772.
25. Cliff K. S. Ong, R. A. Seymour. Pathogenesis of Postoperative Oral Surgical Pain. Anesth Prog. 2003;50(1):5-17.
26. Yu-Feng Xie, Fu-Quan Huo, Jing-Shi Tang. Cerebral cortex modulation of pain. Acta Pharmacol Sin. 2009;30(1):31–41.
27. Mike Brügger, Dominik A. Ettlin, Michael Meier, Thierry Keller, Roger Luechinger, Ashley Barlow, Sandro Palla, Lutz Jäncke, Kai Lutz. Taking sides with pain – lateralization aspects related to cerebral processing of dental pain. Front Hum Neurosci. 2011;5(12):1-13.
28. Eric L. Garland. Pain Processing in the Human Nervous System: A Selective Review of Nociceptive and Biobehavioral Pathways. Prim Care. 2012;39(3):561–571.
29. Vignesh. R, Vishnu Rekha C., Parisa Norouzi Baghkomeh, Sankar Annamalai, D. Ditto Sharmin. Algesia and Analgesia in Pediatric Dentistry. Research J. Pharm. and Tech. 2019; 12(5):2559-2565.
30. Trophimus Gnanabagyan Jayakaran, Vignesh R, Shankar P. Local Anesthetics in Pediatric Dental Practice. Research J. Pharm. and Tech 2019; 12(8): 4066-4070