Author(s):
Cut Aja Nuraskin, Reca, Wirza, Ainun Mardiah, Rivansyah Suhendra, Iskandar Faisal, Teuku Salfiyadi, Cut Mutia
Email(s):
cutaja82@yahoo.co.id
DOI:
10.52711/0974-360X.2021.00999 
Address:
Cut Aja Nuraskin1*, Reca1, Wirza, Ainun Mardiah1, Rivansyah Suhendra2, Iskandar Faisal1, Teuku Salfiyadi1, Cut Mutia1
1Poltekkes Kemenkes Aceh Jl. Soekarno Hatta, Tingkeum, Darul Imarah, Lheu Blang, Banda Aceh, Aceh Besar District, Aceh, 23231, Indonesia.
2Department of Informatics, Faculty of Mathematics and Natural Sciences, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia.
*Corresponding Author
Published In:
Volume - 14,
Issue - 11,
Year - 2021
ABSTRACT:
Indonesia is famously known for its rich plant biodiversity with medicinal properties. Guava (Psidium guajava Linn.) is one of medicinal plants which can be used as alternative for treating diseases. Guava leaf contains flavonoids, saponins, and tannins, that can act as inhibitors against bacteria, antioxidants, and antibacterial. Numerous dental and oral diseases are caused by bacteria, one of which is dental caries. Principally, dental caries can be prevented by maintaining the oral cavity hygiene, chemically or mechanically, using antiseptics possessing antibacterial activities. The aim of this study was to investigate the effectiveness of guava leaves steep water against S. Mutans bacterium using microdilution method. The aim also included the investigation of inhibition concentration of guava leaves steep water. This research was experimental in nature, by using the guava leaves steep water as the sample with various concentrations (0.753%, 1.563%, 3.125%, 6.25%, 12.5%, 25%, 50%, 100%). S. Mutans was obtained from the laboratory of veterinary Universitas Syiah Kuala (Unsyiah). The results of this research revealed that the guava leaves steep water was effective in inhibiting S. Mutans with Minimum Inhibitory Concentration (MIC) of 6.25% In conclusion, we would like to investigate the guava leaves steep water as a mouthwash in our research with a preclinical trial.
Cite this article:
Cut Aja Nuraskin, Reca, Wirza, Ainun Mardiah, Rivansyah Suhendra, Iskandar Faisal, Teuku Salfiyadi, Cut Mutia. Effectiveness of Guava Leaf Steep water against the bacterial growth of S. Mutans with Microdillution Method. Research Journal of Pharmacy and Technology. 2021; 14(11):5745-8. doi: 10.52711/0974-360X.2021.00999
Cite(Electronic):
Cut Aja Nuraskin, Reca, Wirza, Ainun Mardiah, Rivansyah Suhendra, Iskandar Faisal, Teuku Salfiyadi, Cut Mutia. Effectiveness of Guava Leaf Steep water against the bacterial growth of S. Mutans with Microdillution Method. Research Journal of Pharmacy and Technology. 2021; 14(11):5745-8. doi: 10.52711/0974-360X.2021.00999 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-11-24
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