Hiyam Raaof Al-Hamamy, Wafaa Hazim Salih, Nada H. Al-Mudallal
Halhammay@yahoo.com , Wafaahazim@kmc.uobaghdad.edu.iq , Nada_Mudallal@aliraqia.edu.iq
Hiyam Raaof Al-Hamamy1, Wafaa Hazim Salih2, Nada H. Al-Mudallal3
1Assistant Prof. Pathology Dept, Al-Kindy College of Medicine, University of Baghdad.
2Lecturer of Microbiology, Bacteriology, Microbiology Department, Al-Kindy College of Medicine, University of Baghdad., Iraq.
3Assistant Prof. Medical Microbiology Dept., College of Medicine, Al-Iraqia University, Baghdad, Iraq.
Volume - 14,
Issue - 12,
Year - 2021
Background: Ear infections can manifest in many forms depending on site of infection whether external, middle or internal ear and the culprit pathogen whether viral, bacterial or fungal. Acute middle ear infections are usually accompanied by aural discharge. Objective: 1. To get an overview on the bacterial pathogens involved in ear infections. 2. To assess the antibiotic resistance of bacterial pathogens. Methods: A cross sectional study conducted in Al-Kindy Teaching Hospital / Baghdad /Iraq. Swabs taken from 225 patients suffering from aural discharge were tested for culture and sensitivity for the duration of two years 2018-2019. Aural discharge is cultured by inoculating it into blood, MacConkey agar, chocolate agars and Sabouraud agar (for fungi). Then the antibiotic susceptibility and resistance is assessed by (Kirby-Bauer Method). Results: Then, by analyzing the percentage of pathogens involved in ear infections we have found that the highest percentage is for Pseudomonas aeruginosa (51%), followed by Staph, aureus (20%), Proteus vulgaris (11%). Discussion: Cefotaxime, which was known to be an efficient antibiotic against pseudomonas previously, has lost its effectiveness. Similarly, gentamycin is no longer effective against E.coli. Conclusion: Choosing the proper antibiotic in any bacterial infection is of tremendous importance. However, reassessment of antibiotic resistance profiles is vital and should be regarded as a routine task on regular intervals.
Cite this article:
Hiyam Raaof Al-Hamamy, Wafaa Hazim Salih, Nada H. Al-Mudallal. Bacterial Isolates and Antibiotic Susceptibility of Ear Infections in Al-Kindy Teaching Hospital, Baghdad, Iraq. Research Journal of Pharmacy and Technology. 2021; 14(12):6503-6. doi: 10.52711/0974-360X.2021.01124
Hiyam Raaof Al-Hamamy, Wafaa Hazim Salih, Nada H. Al-Mudallal. Bacterial Isolates and Antibiotic Susceptibility of Ear Infections in Al-Kindy Teaching Hospital, Baghdad, Iraq. Research Journal of Pharmacy and Technology. 2021; 14(12):6503-6. doi: 10.52711/0974-360X.2021.01124 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2021-14-12-54
1. Muluye D, Wondimeneh Y, Ferede G, Moges F, Nega T. Bacterial isolates and drug susceptibility patterns of ear discharge from patients with ear infection at Gondar University Hospital, Northwest Ethiopia. BMC Ear Nose Throat Disord. 2013; 13(1):10-.
2. Jawad IH, AL-Jubori KH, Baiee HA. Prevalence and Associated Factors of Under Nutrition among Under-Five Children in Babylon Province, Iraq, 2016. Research Journal of Pharmacy and Technology. 2017; 1000:100.
3. Bowatte G, Tham R, Perret JL, Bloom MS, Dong G, Waidyatillake N, et al. Air Pollution and Otitis Media in Children: A Systematic Review of Literature. Int J Environ Res Public Health. 2018; 15(2):257.
4. Jasiem TMJRJoP, Technology. Isolation of Terpene and Pharmacognostical Study of Iraqi Caper Shrubs (Capparis spinosa) L. 2018; 11(6):2388-92.
5. Woodfield G, Dugdale A. Evidence behind the WHO guidelines: hospital care for children: what is the most effective antibiotic regime for chronic suppurative otitis media in children? Journal of tropical pediatrics. 2008; 54(3):151-6.
6. Patra A, Jha S, Murthy PNJRJoP, Technology. Anthelmintic and antibacterial activities of Hygrophila spinosa T. Anders. Research Journal of Pharmacy and Technology. 2008; 1(4):531-2.
7. Qureishi A, Lee Y, Belfield K, Birchall JP, Daniel M. Update on otitis media - prevention and treatment. Infect Drug Resist. 2014; 7:15-24.
8. Divekar K, Shivakumar Swamy KN, Murugan V, Devgun MJRJoP, Technology. Synthesis and evaluation of some new pyrazole derivatives as antimicrobial agents. Research Journal of Pharmacy and Technology. 2010; 3(4):1039-43.
9. Wasihun AG, Zemene Y. Bacterial profile and antimicrobial susceptibility patterns of otitis media in Ayder Teaching and Referral Hospital, Mekelle University, Northern Ethiopia. Springerplus. 2015; 4:701-.
10. Patil VN, Yadav AG, Bobade A, Athlekar S, SPatil L, Chowdhary AJRJoP, et al. Synthesis and Evaluation of New Benzothiazole Derivatives as Potential Antimicrobial Agents. Research Journal of Pharmacy and Technology. 2010; 3(4):1044-6.
11. Ur Rahman S, Ali T, Ali I, Khan NA, Han B, Gao J. The Growing Genetic and Functional Diversity of Extended Spectrum Beta-Lactamases. Biomed Res Int. 2018; 2018:9519718-.
12. Singh MK, Prathapan A, Nagori K, Ishwarya S, Raghu KJRJoP, Technology. Cytotoxic and Antimicrobial Activity of Methanolic Extract of Boerhaavia diffusa L. Research Journal of Pharmacy and Technology. 2010; 3(4):1061-3.
13. Al-Attar Z. The prevalence and antimicrobial sensitivity of Esbl Escherichia Coli. in clinical isolates. Al-Kindy College Medical Journal 2014; 10(1): 49-52
14. Korsakov K, Vasiliev A, Kozlov S, Salautin V, Moskalenko S, Sivokhina L, et al. The Effect of The Reasil® Humic Health feed Additive on the rate of Antibacterial drugs removal from the Organisms of broiler Chickens. Research Journal of Pharmacy and Technology. 2020; 13(12):6113-9.
15. Arslan IB, Genc S, Kayhan BC, Gumussoy M, Ozel G, Cukurova I. Bacterial change in external auditory canal upon antisepsis with povidone-iodine during tympanoplasty. European Archives of Oto-Rhino-Laryngology. 2015; 272(3):551-5.
16. Vaishali G, Geetha R. The superbug threat. Research Journal of Pharmacy and Technology. 2015; 8:343.
17. Kumar R, Srivastava P, Sharma M, Rishi S, Nirwan PS, Hemwani K, et al. Isolation and antimicrobial sensitivity profile of bacterial agents in chronic suppurative otitis media patients at nims hospital. International Journal of Pharmacy and Biological Sciences. 2013; 3(4).
18. Vinodhini G, Kumar MA, Balamanikandan S, Seenuvasan M. Assessment of antimicrobial property of a secondary metabolite produced by an enriched bacterial culture isolated from soil. Research Journal of Pharmacy and Technology. 2015; 8(1):51-3.
19. Al-Attar Z. The prevalence and antimicrobial resistance of pseudomonas species in patients with chronic suppurative otitis media Al-Kindy College Medical Journal. 2014; 10(1):114-7.
20. Shahid SM, Umar N. Spectrum of Antimicrobial Susceptibility of E. coli and Staphylococcus aureus Isolates from Clinical Samples. Research Journal of Pharmacy and Technology. 2015; 8(10):1399-402.
21. Deepigaa M. Antibacterial resistance of bacteria in biofilms. Research Journal of Pharmacy and Technology. 2017; 10(11):4019-23.
22. Carmine AA, Brogden RN, Heel RC, Speight TM, Avery GS. Cefotaxime. A review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. 1983; 25(3):223-89.
23. Mohamed SH, Elshahed MM, Saied YM. Evaluation of Honey as an antibacterial agent against drug-resistant uropathogenic E. coli strains. Research Journal of Pharmacy and Technology. 2020; 3(8):3720-4.
24. Zhanel GG, Karlowsky JA, Davidson RJ, Hoban DJ. Effect of Pooled Human Cerebrospinal Fluid on the Postantibiotic Effects of Cefotaxime, Ciprofloxacin, and Gentamicin against Escherichia coli. Antimicrobial agents and chemotherapy. 1992; 36(5):1136-9.