Author(s): Chandra Shakar Reddy Nallagouni, Bhagavanth Reddy Gangapuram, Pratap Reddy Karnati


DOI: 10.5958/0974-360X.2021.00185.2   

Address: Chandra Shakar Reddy Nallagouni1, Bhagavanth Reddy Gangapuram2, Pratap Reddy Karnati1*
1Department of Zoology, Osmania University, Hyderabad, India.
2Department of Chemistry, Palamuru University, Hyderabad, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 2,     Year - 2021

The study describes a simple and green method for the synthesis of gold nanoparticles using the leaf extract of Caesalpinia bonducella. UV-Vis spectroscopy (UV-Vis), Fourier transforms infrared spectroscopy (FTIR), X-Ray diffraction (XRD) and Transmission electron microscopy (TEM) was used to characterize the gold nanoparticles. FTIR analysis indicates that- OH groups present in the leaf extract were responsible for the reduction of metal cations into nanoparticles. UV-Vis analysis showed a Surface Plasmon Resonance in the range of 518-538 nm due to the formation of gold nanoparticles. XRD studies indicated that the nanoparticles were crystalline in nature with face centred cubic geometry. TEM analysis revealed that the shape of the gold nanoparticles was in spherical forms and the average of particle size was 11±2 nm. In addition, the nanoparticles showed good antimicrobial activity against gram-positive and gram-negative bacterias. Thus, the study emphasizes that the green synthesized AuNPs could be considered as a promising antimicrobial agents.

Cite this article:
Chandra Shakar Reddy Nallagouni, Bhagavanth Reddy Gangapuram, Pratap Reddy Karnati. Green synthesis of Gold Nanoparticles using leaf extract of Caesalpinia bonducella and its biological Applications. Research J. Pharm. and Tech. 2021; 14(2):1037-1040. doi: 10.5958/0974-360X.2021.00185.2

Chandra Shakar Reddy Nallagouni, Bhagavanth Reddy Gangapuram, Pratap Reddy Karnati. Green synthesis of Gold Nanoparticles using leaf extract of Caesalpinia bonducella and its biological Applications. Research J. Pharm. and Tech. 2021; 14(2):1037-1040. doi: 10.5958/0974-360X.2021.00185.2   Available on:

1.    Vilchis-Nestor AR., Sánchez-Mendieta V, Camacho-López MA, Gómez-Espinosa RM, Camacho-López MA, Arenas-Alatorre JA. Solventless synthesis and optical properties of Au and Ag nanoparticles using Camellia sinensis extract. Mater. Lett. 2008; (62): 3103-3105.
2.    Meena Kumari M, Jacob J, Philip D. Green synthesis and applications of Au-Ag bimetallic nanoparticles. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2015; (137): 185-192.
3.    Giljohann DA, Seferos DS, Daniel WL, Massich MD, Patel PC and Mirkin CA. Angew. Chem. Int. Ed. 2010; (49): 3280–3294.
4.    L. Dykman and N. Khlebtsov, Chem. Soc. Rev. 2012; (41): 2256-2282.
5.    Kim H, Beack S, Han S, Shin M, Lee T, Park Y, Kim KS, Yetisen AK, Yun SH, Kwon W and Hahn SK, Adv. Mater. 2018; (30): 1701460.
6.    Kharissova OV, Dias HVR, Kharisov BI, Pérez BO, Pérez VMJ. The greener synthesis of nanoparticles. Trends in Biotechnology. 2013; (31): 240-248.
7.    Logeswari P, Silambarasan S, Abraham J. Eco friendly synthesis of silver nanoparticles from commercially available plant powders and their antibacterial properties. Sci. Iran. 2013; (20): 1049-1054.
8.    Nadagouda MN, Iyanna N, Lalley J, Han C, Dionysiou DD, Varma RS. Synthesis of silver and gold nanoparticles using antioxidants from blackberry, blueberry, pomegranate, and turmeric extracts. ACS Sustain. Chem. Eng. 2014; (2): 1717-1723.
9.    Dipankar C and Murugan S. The green synthesis, characterization and evaluation of the biological activities of silver nanoparticles synthesized from Iresine herbstii leaf aqueous extracts. Colloids Surf. B. 2012; (98): 112-119.
10.    Arumai Selvan D, Mahendiran D, Senthil Kumar R, Kalilur Rahiman A. Garlic, green tea and turmeric extracts-mediated green synthesis of silver nanoparticles: Phytochemical, antioxidant and in vitro cytotoxicity studies. J. Photochem. Photobiol. B. 2018; (180): 243-252.
11.    Iravani S. Green synthesis of metal nanoparticles using plants. Green Chem. 2011; (13):2638-2650.
12.    Neogi NC, Nayak KA. Biological investigation of Caesalpinia bonducella F. Ind J Pharmacol. 1958; (20):95-100.
13.    Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Roy C. Screening of Indian medicinal plant for biological activity. Ind J Expt Biol 1968; (6):232-247.
14.    Raghunathan K, Mitra R, Karanja. In. Raghunathan K, Mitra. R. Pharmacognosy of Indogenous Drugs. Part-1, Central Councial for Research in Ayurveda and Siddha. New Delhi, India, 1982; 484-510.
15.    Adesina SK. Studies on some plants used as anticonvulsants in ameridian and african traditional medicine. Fitoterapia. 1982;(53):147-162.
16.    Iyengar MA, Pendse GS. Antidiarrheal activity of the nut of Caesalpinia bonducella F. Ind J Pharmacol. 1965; (27):307-308.
17.    Gayaraja S, Shinde S, Agarwal SL. Antiasthmatic properties of Caesalpinia bonducella Leaves. Ind J Pharmacol 1978;(10):86-88.
18.    Gupta M, Mazumder UK, Sambath Kumar R. Hepatoprotective effect and antioxidant role of C. bonducella on Paracetamol-induced hepatic damage in rats. Natural product Sciences. 2003; (9):186-191.
19.    Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: a review. J Pharm Anal. 2016; (6):71-79.
20.    Reddy GB, Ramakrishna D, Madhusudhan A., Ayodhya D, Venkatesham M, Veerabhadram, G. Catalytic Reduction of p-Nitrophenol and Hexacyanoferrate (III) by Borohydride Using Green Synthesized Gold Nanoparticles. J. Chin. Chem. Soc. 2015; (62): 420-428.
21.    Reddy NCS, Nageshwar M and Reddy GB. Biosynthesis and characterization of gold nanoparticle from Coccinia grandis and its catalytic activity. Int J Pharm Sci & Res. 2019; 10(9): 4391-95. doi: 10.13040/IJPSR.0975-8232.10(9).4391-95.
22.    Cho KH, Park JE, Osaka T, Park SG. The study of antimicrobial activity and preservative effects of nano silver ingredient. Electrochim Acta. 2005 (51):956-960.
23.    Xu W, Jin W, Lin L, Zhang C, Li Z, Li Y, Song R, Li B. Green synthesis of xanthan conformation-based silver nanoparticles: antibacterial and catalytic application. Carbohydr Polym.2014; (101):961-967.

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