Author(s): Assaf H. Tawfeeq, Bushra B. Qassim


DOI: 10.52711/0974-360X.2021.00341   

Address: Assaf H. Tawfeeq1, Bushra B. Qassim2
1Ph.D. Student, Department of Chemistry, College of Science, University of Baghdad, Iraq.
2Prof. Analytical Chemistry, Department of Chemistry, College of Science, University of Baghdad, Iraq.
*Corresponding Author

Published In:   Volume - 14,      Issue - 4,     Year - 2021

A newly, simple and precise Spectrophotometric methods were improved for the determination of Ceftriaxone (XONE) in pure and pharmaceutical formulations which Involved the reaction of FeCl3/(FeNO3)3 with (XONE) to yield a dark-blue greenish dissolved composite which has maximum absorbance at 780nm. This process was sensitive, precise and accurate where the limit of detection was (0.08µg/ml) and the RSD% was 0.65% and Recovery was 95%. Various chemical and physical conditions that affected the reaction have been elaborate. The calibration curve was straight within the concentration range 0.5-12µg/mL. Stability constant, Molar absorptivity and Sandell’s sensitivity were (5.1x109, 121 and 0.0045) respectively The design procedure was appropriate efficiently for the estimate of XONE and the results possess were favorably comparison with those addicted by a reference method of British Pharmacopeia, and there was no important difference between the obtained results, regarding accuracy and precision at the 95% confidence level.

Cite this article:
Assaf H. Tawfeeq, Bushra B. Qassim. New Spectrophotometric procedure for Assaying Ceftriaxone. Research Journal of Pharmacy and Technology. 2021; 14(4):1928-2. doi: 10.52711/0974-360X.2021.00341

Assaf H. Tawfeeq, Bushra B. Qassim. New Spectrophotometric procedure for Assaying Ceftriaxone. Research Journal of Pharmacy and Technology. 2021; 14(4):1928-2. doi: 10.52711/0974-360X.2021.00341   Available on:

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