Author(s): Divya Yada, T. Sivakkumar, M. Sudhakar


DOI: 10.52711/0974-360X.2021.00489   

Address: Divya Yada1*, T. Sivakkumar2, M. Sudhakar1
1Department of Pharmaceutical Chemistry, Malla Reddy College of Pharmacy, Maisammaguda, Dhulapally, Secunderabad - 14.TS.
2Department of Pharmacy, Annamalai University, Annamalai Nagar, Chidambaram TN.
*Corresponding Author

Published In:   Volume - 14,      Issue - 5,     Year - 2021

The current line of investigation was focused at perusing the presence of phytochemical constituents, investigation of total phenol and flavonoid content, the antioxidant potential of various extracts of Caralluma adscendens whole plant using various in-vitro assays. The dried plant powder was extracted with various solvents based on polarity (Pet ether, Chloroform, Ethyl acetate, Ethanol and Aqueous) by hot continuous extraction in Soxhlet's apparatus and Extracts were dried. Phytoconstituents present in each extract was examined by performing preliminary phytochemical screening. Total Phenolic Content (TPC), Total Flavonoid Content (TFC) and Antioxidant potential for crude extracts were studied by DPPH, nitric oxide scavenging and FRAP methods. The total phenolic content and flavonoid content of Ethanolic extract of plant was found to be 80.08±0.629mg and 70.88±1.170mg of GAE and Quercetin equivalents respectively. The Ethanolic extract exhibited potent antioxidant activity as determined by 2,2-diphenyl-1-picrylhydrazyl(DPPH), nitric oxide scavenging and ferric reducing antioxidant power assays(FRAP) than the other extracts. The IC50 values for the Ethanolic extract of Caralluma adscendens was found to be 214.765±0.224 µg/ml and 215.928±0.506µg/ml by DPPH and nitric oxide scavenging assays respectively.

Cite this article:
Divya Yada, T. Sivakkumar, M. Sudhakar. Phytochemical Evaluation and In-vitro Antioxidant Potential of whole plant of Caralluma adscendens. Research Journal of Pharmacy and Technology. 2021; 14(5):2774-8. doi: 10.52711/0974-360X.2021.00489

Divya Yada, T. Sivakkumar, M. Sudhakar. Phytochemical Evaluation and In-vitro Antioxidant Potential of whole plant of Caralluma adscendens. Research Journal of Pharmacy and Technology. 2021; 14(5):2774-8. doi: 10.52711/0974-360X.2021.00489   Available on:

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