Author(s): Deepankar Sharma, Purnima Nag

Email(s): purnima_nag007@yahoo.com

DOI: 10.52711/0974-360X.2022.00005   

Address: Deepankar Sharma, Purnima Nag*
Department of Chemistry, Jaipur National University, Jaipur-302017, Rajasthan, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 1,     Year - 2022


ABSTRACT:
The interaction of Copper and Nickel chloride with oximes of 2-Acetylfuran, 2-Acetylthiophene and 2-Acetylpyridine in absence of an external base resulted in formation of the complexes of the type [MCl2L2] (A) and [MCl2L2].H2O (A.H2O) {Here M: Cu or Ni; L: HON=C(CH3) Ar; where Ar = C4H3S, C4H3O or C5H4N}. The parent ligands were synthesized by green method using water as a solvent. Complexes were characterized by elemental analysis, 1H-NMR, IR spectral studies and these spectra were compared with that of free ligands. Spectral measurements suggest an octahedral or distorted octahedral geometry for all these complexes. The in-vitro Antifungal activity of all these complexes has proven that they are active against Candida albicans even at lower concentrations.


Cite this article:
Deepankar Sharma, Purnima Nag. In-vitro Antifungal Evaluation of Some Cu and Ni Complexes. Research Journal of Pharmacy and Technology. 2022; 15(1):24-8. doi: 10.52711/0974-360X.2022.00005

Cite(Electronic):
Deepankar Sharma, Purnima Nag. In-vitro Antifungal Evaluation of Some Cu and Ni Complexes. Research Journal of Pharmacy and Technology. 2022; 15(1):24-8. doi: 10.52711/0974-360X.2022.00005   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-1-5


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