Author(s): Artono, Rahmi Surayya, Nyilo Purnami, Edi Handoko

Email(s): nyilo@fk.unair.ac.id

DOI: 10.52711/0974-360X.2022.00282   

Address: Artono1,2, Rahmi Surayya2, Nyilo Purnami2*, Edi Handoko3
1Doctoral Program, Faculty of Medicine, Universitas Airlangga, Jl. Mayjen Prof. Dr. Moestopo No.47, Pacar Kembang, Tambaksari, Surabaya, Jawa Timur 60132, Indonesia.
2Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Airlangga, Dr Soetomo General Academic Hospital. Jl. Mayjen Prof. Dr. Moestopo No.6-8, Airlangga, Gubeng, Surabaya, Jawa Timur 60286, Indonesia.
3Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, Universitas Brawijaya, Veteran Malang Road, Malang, Jawa Timur 65145, Indonesia.
*Corresponding Author

Published In:   Volume - 15,      Issue - 4,     Year - 2022


ABSTRACT:
Introduction: Chronic suppurative otitis media (CSOM) is a chronic inflammation in the middle ear and mastoid space that repeatedly secretes through the perforated membrane of tympanic disease over three months. This disease is a critical cause of hearing in developing countries. The prevalence of CSOM in Indonesia is 3.8%. Improper use of antibiotics leads to germicidal incidence. Understanding the pattern of germs and their antibiotic sensitivity will lead to a rational choice of antibiotics to prevent the emergence of resistance. Aim: to report the microbiological profile and sensitivity patterns in CSOM patients in our department. Materials and Methods: This is a retrospective descriptive study conducted on 45 patients from September 2019 - March 2020 at the ENT-KL Department of Dr Soetomo Surabaya Indonesia. Forty-five samples were collected from CSOM patients who underwent mastoidectomy. Specimens were collected from these patients, examination, isolation, examination and isolation antibiogram were carried out according to standard procedures. Results: A total of 45 samples were obtained from this study, and all (57.77%) of the patients were identified as CSOM cases with cholesteatoma. The number of women is 62.3% more than men, and the age group 12 to 16 (20.0%) is the most reported. There were 75.6% perforations in the tympanic membrane, and a central perforation was primarily found (35.6%). Most of the Schuller mastoid X-ray results showed sclerotic features in 29 patients (59.2%). Of the 45 ear swabs, about 68.89% of the surgical materials gave positive culture results, the remaining 31.11%. There was no microbial growth, where most of the growth of monomicrobial bacteria (57.8%). Of the isolates that grew, 70.58% were identified as the group of gram-negative bacteria, with Pseudomonas Aerogenosa isolates being the most common (44.11%). Conclusion: The sensitivity test showed the most sensitivity to Meropenam, Amikacin, Piperacillin-Tazobactam, Ceftasidim and Cefoperazone-Sulbactam Cefotaxime and Ceftriaxone showed lower sensitivity.


Cite this article:
Artono, Rahmi Surayya, Nyilo Purnami, Edi Handoko. Microbiological profile with Antibiotic Sensitivity Pattern for Chronic Suppurative Otitis Media in A Tertiary Hospital, Indonesia. Research Journal of Pharmacy and Technology. 2022; 15(4):1683-8. doi: 10.52711/0974-360X.2022.00282

Cite(Electronic):
Artono, Rahmi Surayya, Nyilo Purnami, Edi Handoko. Microbiological profile with Antibiotic Sensitivity Pattern for Chronic Suppurative Otitis Media in A Tertiary Hospital, Indonesia. Research Journal of Pharmacy and Technology. 2022; 15(4):1683-8. doi: 10.52711/0974-360X.2022.00282   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2022-15-4-48


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