Author(s): Diksha Singh, Kashmira J. Gohil, Rekha T. Rajput, Vikash Sharma


DOI: 10.52711/0974-360X.2022.00553   

Address: Diksha Singh1, Kashmira J. Gohil1, Rekha T. Rajput2, Vikash Sharma1
1Department of Pharmacology, Anand College of Pharmacy, SGI Agra - 282007.
2Department of Pharmacognosy, Anand College of Pharmacy, SGI Agra - 282007.
*Corresponding Author

Published In:   Volume - 15,      Issue - 7,     Year - 2022

Prunus amygdalus (Batsch.) is an important medicinal plant and belongs to the family Rosaceae. It is known as Badam in Hindi and almond in English. The nutritional and medicinal properties of badam fruit are related to its kernel. It has been therapeutic uses for constipation, headache, heart weakness, diarrhea, sedative, amnesia, peptic ulcer, leprosy, polyuria, facial paralysis, Cough, Sexual disability, leprosy, etc. Kaempferol-3-xylosylglucoside and Quercitin are common chemical properties. Almond oil contains the source of vitamin A, B1, B2, B6, E, D, and also contains calcium and magnesium. The preclinical studies mainly depend on flavonoids, phenol, alkaloid, and saponins, tannins. The present review provides comprehensive information of the plant on its Pharmacognostical and Pharmacological profile including its preclinical and clinical studies/ clinical trial and nutritional value in different varieties.

Cite this article:
Diksha Singh, Kashmira J. Gohil, Rekha T. Rajput, Vikash Sharma. Almond (Prunus amygdalus Batsch.): A Latest Review on Pharmacology and Medicinal uses. Research Journal of Pharmacy and Technology. 2022; 15(7):3301-8. doi: 10.52711/0974-360X.2022.00553

Diksha Singh, Kashmira J. Gohil, Rekha T. Rajput, Vikash Sharma. Almond (Prunus amygdalus Batsch.): A Latest Review on Pharmacology and Medicinal uses. Research Journal of Pharmacy and Technology. 2022; 15(7):3301-8. doi: 10.52711/0974-360X.2022.00553   Available on:

1.    Martinez-Gomez, Pedro, et al. "Almond." Fruits and nuts. Springer, Berlin, Heidelberg.2007;229-242.
2.    Abdullah, Mohd Khalid, and Mohd Kashif Hussain. "Badam (Prunus amygdalus Bail.): A fruit with medicinal properties." International Journal of Herbal Medicine. 2017; 5(5): 114-117
3.    Mushtaq, Ayesha, et al. "Almond (Purunus amygdalus L.): A review on health benefits, nutritional value and therapeutic applications." International Journal of Chemical and Biochemical Sciences.2015;8:103-106
4.    El Hawary, Seham S., et al. "Study of Nutritional Contents of Prunus Amygdalus Batsch Seeds." Egyptian Journal of Hospital Medicine.2014;57: 437-443
5.    Esfahlan, Ali Jahanban, Rashid Jamei, and Rana Jahanban Esfahlan. "The importance of almond (Prunus amygdalus L.) and its by-products." Food chemistry. 2010; 120(2): 349-360. doi: 10.1016/j.foodchem.2009.09.063
6.    Balta, Mehmet Fikret. "Fatty acid profiles for almond (Prunus amygdalus Batsch) genotypes with different kernel taste and formation." Iğdır Univ. J. Inst. Sci. Tech. 2013;3(1): 17-24
7.    Masihuzzaman, Ansari Mohd, Munshi Younus Iftikhar, and Khanum Farheen. "Badam shireen (Prunus dulcis Mill): A ghiza-e-dawaee and immunomodulator: A latest review." International Journal of Unani and Integrative Medicine 2020; 4(2): 09-14
8.    Liu, Zhibin, et al. "In vitro and in vivo evaluation of the prebiotic effect of raw and roasted almonds (Prunus amygdalus)." Journal of the Science of Food and Agriculture. 2016;96(5): 1836-1843. ) doi: 10.1002/jsfa.7604
9.    Geng, Huiling, et al. "Extraction, chemical composition, and antifungal activity of essential oil of bitter almond." International journal of molecular sciences. 2016;17(9):1421. doi:10.3390/ijms17091421
10.    Karatay, Hüseyin, et al. "Major fatty acids composition of 32 almond (Prunus dulcis [Mill.] DA Webb) genotypes distributed in East and Southeast of Anatolia." Türk Biyokimya Dergisi [Turkish Journal of Biochemistry–Turk J Biochem]. 2014; 39(3):307–316
11.     Bennet R, Arun A, Faraday MK. A Study on the Nutritive Analysis of Almond Intake for Optimal Muscle Hypertrophy. Research Journal of Pharmacy and Technology. 2018 Oct 31;11(10):4539-42. doi: 10.5958/0974-360x.2018.00830.2
12.    Daniel Silas Samuel, R.V. Geetha. Antioxidant Activity of Dry Fruits: A Short Review. Research Journal of Pharmacy and Tecgnology. 2014 Nov; 7(11): 1319-1322.
13.    Moradi, Behzad, et al. "A systematic review of phytochemical and phytotherapeutic characteristics of bitter almond." International Journal of Pharmaceutical and Phytopharmacological Research .2017;7(2):1-9. doi: 10.24896/eijppr.2017721
14.    Akubude, Vivian C., and Kevin N. Nwaigwe. "Economic importance of edible and non-edible almond fruit as bioenergy material: a review." American Journal of Energy Science.2016; 3(5): 31-39.
15.    Siriwardhana, Subhashinee SKW, and Fereidoon Shahidi. "Antiradical activity of extracts of almond and its by-products." Journal of the American Oil Chemists' Society .2002;79(9): 903-908
16.    Esfahlan, Ali Jahanban, and Rashid Jamei. "Properties of biological activity of ten wild almond (Prunus amygdalus L.) species." Turkish Journal of Biology. 2012;36(2): 201-209. doi:10.3906/biy-1101-174
17.    Sahib, Zena Hasan. "Assessment of anxiolytic activity of nuts of Prunus amygdalus Dulcis (almond) in mice." Medical Journal of Babylon .2014;11(4): 817-824.
18.    Oliveira, Ivo, et al. "Effects of Different Processing Treatments on Almond (Prunus dulcis) Bioactive Compounds, Antioxidant Activities, Fatty Acids, and Sensorial Characteristics." Plants.2020;9(1):1627
19.    Milbury, Paul E., et al. "Determination of flavonoids and phenolics and their distribution in almonds." Journal of agricultural and food chemistry. 2006;54(14):5027-5033
20.    Beck, John J., et al. "In situ seasonal study of the volatile production of almonds (Prunus dulcis) var.‘Nonpareil’and relationship to navel orangeworm." Journal of agricultural and food chemistry .2009;57(9):3749-3753
21.    Alasalvar, Cesarettin, and Bradley W. Bolling. "Review of nut phytochemicals, fat-soluble bioactives, antioxidant components and health effects." British Journal of Nutrition. 2015;113(S2): S68-S78
22.    Yada, Sylvia, Guangwei Huang, and Karen Lapsley. "Natural variability in the nutrient composition of California-grown almonds." Journal of food composition and analysis. 2013;30(2):80-85
23.    Summo, Carmine, et al. "Evaluation of the chemical and nutritional characteristics of almonds (Prunus dulcis (Mill). DA Webb) as influenced by harvest time and cultivar." Journal of the Science of Food and Agriculture. 2018;98(15):5647-5655
24.    Barreca, Davide, et al. "Almonds (Prunus dulcis Mill. DA Webb): a source of nutrients and health-promoting compounds." Nutrients. 2020;12(3):672
25.    Akubude, VIVIAN Chimezie, et al. "Almond oil: powerhouse of nutrients." Agricultural Engineering International: CIGR Journal. 2020;22(3):190-201
26.    Sovilj, Milan N. "Critical review of supercritical carbon dioxide extraction of selected oil seeds." Acta periodica technologica. 2010;41:105-120
27.    Adu, Oluwatosin B., et al. "Effect of processing on the quality, composition and antioxidant properties of Terminalia catappa (indian almond) seed oil." African Journal of Food, Agriculture, Nutrition and Development. 2013;13(3): 7662-7678
28.    Garcıa-Pascual, P., et al. "Influence of storage conditions on the quality of shelled and roasted almonds." Biosystems engineering. 2003;84(2):201-209
29.    Bolaji, O. S., O. O. Ogunmola, and A. Sodamade. "Chemical profile of the mesocarp of three varieties of Terminalia catappa L (almond tree)." IOSR Journal of Applied Chemistry. 2013;4(4):10-12
30.    Ellis, Peter R., et al. "Role of cell walls in the bioaccessibility of lipids in almond seeds." The American journal of clinical nutrition. 2004;80(3):604-613
31.    Khan, Shaukat Ali, A. N. J. U. M. Perveen, and GHULAM RASOOL Sarwar. "Germination capacity and viability in pollen of Prunus amygdalus Batsch (Rosaceae)." Pak. J. Bot. 2013;45(4):1383-1385
32.    Ali, Ehsan, et al. "Aflatoxin contamination and mineral profile of almond seeds." Mycopath. 2009;7(1):39-44
33.    Som K. Madhvi, Manik Sharma, Javaid Iqbal, Mohd Younis, Razda Sheikh. Phytochemical analysis, Total Flavoniud, Phenolic Contents and Antioxidant activity pf extracts from the Leaves of Rhododendron arboretum. Research Journal of Pharmacy and Technology. 2020; 13(4): 1701- 1706. doi: 10.5958/0974-360X.2020.00307.8
34.    Hanine, H., et al. "Pomological and biochemical characterization of almond cultivars in Morocco." Turkish Journal of Agricultural and Natural Sciences.2014;1:743-753
35.    Akram, M., et al. "Hypocholestrolemic activity of plants: a review." International Journal of Agronomy and Plant Production. 2013;4(11):2906-11
36.    Salawu, R. A., et al. "Comparative study of the nutritional, phytochemical and mineral compositions of the nuts of tropical almond (Terminalia catappa) and sweet almond (Prunus amygdalus)." Ruhuna Journal of Science.2018;9:70-77
37.    Takeoka, Gary R., and Lan T. Dao. "Antioxidant constituents of almond [Prunus dulcis (Mill.) DA Webb] hulls." Journal of Agricultural and Food Chemistry.2003;51(2):496-501
38.    Sfahlan, Ali Jahanban, et al. "Antioxidants and antiradicals in almond hull and shell (Amygdalus communis L.) as a function of genotype." Food Chemistry. 2009;115(2):529-533
39.    Qureshi, Muhammad Nasimullah, Sodik Numonov, and Haji Akber Aisa. "Chemical and Pharmacological Evaluation of Hulls of Prunus dulcis Nuts." International journal of analytical chemistry.2019;1-7
40.    Thebo, N., et al. "Therapeutic and antioxidant potential in the shell extract of Prunus amygdalus against dermal mycosis." Medicinal and Aromatic Plants. 2012;1(6):1-4
41.    Teotia, S. U. N. I. T. A., M. Singh, and M. C. Pant. "Effect of Prunus Amyqdalus Seeds on Lipid Profile." Indian journal of physiology and pharmacology. 1997;41:383-389
42.    Jadaan, Mohammad S., Atheer A. Khashan, and Omar Salim Ibrahim. "Treatment of Hyperlipidemia Induced in Rats by Sweet Almond (SA) Watery Extract (Prunus Amygdalus) and Compares with Atorvastatin." Systematic Reviews in Pharmacy. 2021;12(1):1050-1052
43.    Kulkarni, Kirti S., S. B. Kasture, and S. A. Mengi. "Efficacy study of Prunus amygdalus (almond) nuts in scopolamine-induced amnesia in rats." Indian Journal of Pharmacology. 2010;42(3):168-173
44.    Haider, Saida, Z. Batool, and D. J. Haleem. "Nootropic and hypophagic effects following long term intake of almonds (Prunus amygdalus) in rats." Nutricion hospitalaria. 2012;27(6):2109-2115
45.    Shah, K. H., et al. "Evaluation of antidiabetic activity of Prunus amygdalus Batsch in streptozotocin induced diabetic mice." Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2011;2(2):432-434
46.    Jabeen, Aisha, et al. "In Vivo Study on Laxative Effect of Prunus amygdalus Oil." International Journal of Medical Research and Health Sciences.2019;8(3):121-125
47.    Kazrani, Hamid Reza, and Seddigheh Jalali. "Laxative effect of bitter almond (Amygdalus communis var. amara)." Iranian Journal of Veterinary Science and Technology. 2014;6(1):37-47
48.    Al-Sayari A, Ghazwani M, Alhamhoom Y, Almaghaslah D, Louis JV, Gurusamy N. The antidepressant-like effect of almond oil: An additive effect with lavender oil. Biomedical Research. 2018; 29: 3402-3407  
49.    Sachdeva, M. K., and T. Katyal. "Abatement of detrimental effects of photoaging by Prunus amygdalus skin extract." International Journal of Current Pharmaceutical Research. 2011;3(1):57-59
50.    Jia, Xiao-Yan, et al. "Hepatoprotective effects of almond oil against carbon tetrachloride induced liver injury in rats." Food chemistry. 2011;125(2):673-678
51.    Mahmood, Hasanain Sh, et al. "The Enhancement Effect of Olive and Almond oils on Permeability of Nimesulide as Transdermal Gel." International Journal of Pharmaceutical Research. 2019;11(1):1200-6
52.    Nandagopal Anitha et al. “Neuroprotective effect of polyherbal formulation in parkinson’s animal model”. Asian journal of pharmaceutical and cilinical research.2020;13(3): 121-125
53.    Arena, Adriana, et al. "Immunomodulatory and antiviral activity of almond skins." Immunology letters. 2010;132:18-23
54.    Mandalari, G., et al. "Polyphenol and nutrient release from skin of almonds during simulated human digestion." Food chemistry. 2010;122:1083-1088
55.    Mandalari, G., et al. "Potential prebiotic properties of almond (Amygdalus communis L.) seeds." Applied and environmental microbiology. 2008;74(14):4264-4270
56.    Thebo, Nasreen, et al. "Clinical study of the prunus dulcis (Almond) shell extract on tinea capitis infection." Natural Products Chemistry and Research.2014;2(3):1-5
57.    Berryman, Claire E., et al. "Effects of daily almond consumption on cardiometabolic risk and abdominal adiposity in healthy adults with elevated LDL‐cholesterol: a randomized controlled trial." Journal of the American Heart Association . 2015;4:e000993
58.    Jenkins, David JA, et al. "Almonds reduce biomarkers of lipid peroxidation in older hyperlipidemic subjects." The Journal of nutrition. 2008;138(5):908-913
59.    Berryman, Claire E., et al. "Effects of almond consumption on the reduction of LDL-cholesterol: a discussion of potential mechanisms and future research directions." Nutrition reviews. 2011;69(4):171-185
60.    Jenkins, David JA, et al. "Almonds decrease postprandial glycemia, insulinemia, and oxidative damage in healthy individuals." The Journal of nutrition. 2006;136(12):2987-2992
61.    Cohen, Ashley E., and Carol S. Johnston. "Almond ingestion at mealtime reduces postprandial glycemia and chronic ingestion reduces hemoglobin A1c in individuals with well-controlled type 2 diabetes mellitus." Metabolism. 2011;60(9):1312-1317
62.    Jamshed, Humaira, et al. "Almond supplementation reduces serum uric acid in coronary artery disease patients: a randomized controlled trial." Nutrition journal. 2015;15(1):1-5
63.    Li, Ning, et al. "Almond consumption reduces oxidative DNA damage and lipid peroxidation in male smokers." The Journal of nutrition. 2007;137(12):2717-2722
64.    Rajaram, Sujatha, Kristianne M. Connell, and Joan Sabaté. "Effect of almond-enriched high-monounsaturated fat diet on selected markers of inflammation: a randomised, controlled, crossover study." British journal of nutrition. 2010;103(6):907-912
65.    Anonymous. The Wealth of India. Vol. VΙΙΙ. CSIR, New Delhi. 1969: 250-255.
66.    Anonymous. Standardization of Single Drugs of Unani Medicine. Part Ι, CCRUM, Ministry of H and FW, Govt. of India, New Delhi. 1987: 23-27.
67.    Gayathri M, Mithra Chandrasekaran, Arun Radhakrishnan, Gowthamarajan Kuppusamy, Sachin Kumar Singh. Optimizing Badam gum towards tableting excipients. Research Journal of Pharmacy and Technology. 2020; 13(12):6176-6181. doi: 10.5958/0974-360X.2020.01077.X
68.    Das SK, Dhake AS, Nayak A, Das NB, Pandeya SN. Antibacterial and Antifungal Activity of Aerial Part of Plant Ammannia baccifera Linn. Research Journal of Pharmacy and Technology. 2011;4(3):430-2.
69.    Shobana G, Sivaelango G, Kumaravel P. Evaluation of antihyperlipidaemic effect of macrotyloma uniflorum seed extract in experimental hyperlipidaemia. Research Journal of Pharmacy and Technology. 2012;5(3):353-6.
70.    Pandeya SN, Kumar R, Kumar A, Pathak AK. Antidiabetics Review on Natural Products. Research Journal of Pharmacy and Technology. 2010;3(2):300-18.
71.    Dhevi R, Gayathri K. Therapeutic Herbal Plants: A Review of Selected Animal Models for Coronary Heart Disease. Research Journal of Pharmacy and Technology. 2018;11(11):5197-204.
72.    Vineela S, Thakur SR. Sinapic acid ameliorates Acrylamide induced Neurotoxicity through inhibition of oxidative stress in rats. Research Journal of Pharmacy and Technology. 2020 Dec 18;13(12):6009-16.
73.    Rajasekaran A, Sivagnanam G, Xavier R. Nutraceuticals as therapeutic agents: A Review. Research Journal of Pharmacy and Technology. 2008;1(4):328-40.

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