Author(s):
Fadhel Ibrahem Aljabari, Haider Abdulkareem Almashhadani, Marowah H. Jehad, Mustafa M. Kadhim
Email(s):
h_r200690@yahoo.com , haideralmashhdani@alrasheedcol.edu.iq
DOI:
10.52711/0974-360X.2023.00122 
Address:
Fadhel Ibrahem Aljabari 1, Haider Abdulkareem Almashhadani2,5*, Marowah H. Jehad3, Mustafa M. Kadhim4,6
1Department of Dentistry, Dijlah University College, Baghdad, Iraq.
2Department of Dentistry, Al-Rasheed University College, Baghdad, Iraq.
3Department of Dentistry, Al-Farabi University College, Baghdad, Iraq.
4College of Dentistry, Al- Farahidi University, Baghdad, Iraq.
5College of technical engineering, The Islamic University, Najaf, Iraq.
6Medical Laboratory Techniques Department, Al-Turath University College, Baghdad, Iraq.
*Corresponding Author
Published In:
Volume - 16,
Issue - 2,
Year - 2023
ABSTRACT:
Metronidazole-MIPs were prepared by using (MDZ) as the template as well as allylchloride (AYC) or allylbromide (AYB) as monomer, used (TMPTA) tri-methylol propane tri-acrylate or ethylene glycol di-methyl acrylate (EGDMA) as cross-linker and initiator used (BP) benzyl peroxide. By using different plasticizers (di butyl Phthalate (DBPH), Nitrobenzene (NB), oleic acid (OA) and paraffin) for MDZ-MIP1 and (Di-butyl sebecate (DBS), Di-methyl acrylate (DMA), Tributylphosphate(TBP) and Tris(ethylhexyl phosphate (TEHP) ) for MDZ-MIP2. Membranes of MIPs were prepared in PVC matrix. The characterizations of each electrode were determined The Slope range from (55.083 - 43.711) mV/decade, Limit of Detection (8 X 10 -4- 2 X 10-6) and Linearity range of electrodes MIPs from (1 X 10-5 - 1 X 10 -1). Stable Signe of electrode pH from (2.5-9) and study the selectivity with additives of drugs synthesis (Glucose, Calcium stearate, sodium benzoate and benzoic acid) demonstrate strong selectivity.
Cite this article:
Fadhel Ibrahem Aljabari, Haider Abdulkareem Almashhadani, Marowah H. Jehad, Mustafa M. Kadhim. Synthesis and Characterization of Molecularly Imprinted Polymers for Metronidazole by using Allyl Chloride and Allyl Bromide as Monomers. Research Journal of Pharmacy and Technology 2023; 16(2):715-0. doi: 10.52711/0974-360X.2023.00122
Cite(Electronic):
Fadhel Ibrahem Aljabari, Haider Abdulkareem Almashhadani, Marowah H. Jehad, Mustafa M. Kadhim. Synthesis and Characterization of Molecularly Imprinted Polymers for Metronidazole by using Allyl Chloride and Allyl Bromide as Monomers. Research Journal of Pharmacy and Technology 2023; 16(2):715-0. doi: 10.52711/0974-360X.2023.00122 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-2-41
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