Author(s): Rasha Eldalawy, Rana Hussein Kutaif, Tahany Amir Tawfeeq, Mohammed Shamil Fayyadh

Email(s): rashaeldalawy@uomustansiriyah.edu.iq , rana.hussein@turath.edu.iq , tahaniamir@uomustansiriyah.edu.iq

DOI: 10.52711/0974-360X.2023.00555   

Address: Rasha Eldalawy1, Rana Hussein Kutaif2, Tahany Amir Tawfeeq1, Mohammed Shamil Fayyadh2
1Department of Pharmacognosy and Medicinal Plants, College of Pharmacy, Mustansiriyah University, Baghdad – Iraq.
2Department of Pharmacy, Al Turath University College, Baghdad – Iraq.
*Corresponding Author

Published In:   Volume - 16,      Issue - 7,     Year - 2023


ABSTRACT:
Caffeine is a widely consumed pharmacologically active substance around the world, Caffeine is a purine alkaloid derived from methylxanthine that is readily permeable through the blood-brain barrier and stimulates the adenosine receptors in the brain leading to its central nervous system stimulant activity. Most people regulate their caffeine consumption in accordance with the objective and subjective effects produced from the methylxanthine, However, individual response to caffeine varies greatly from person to person due to the variation in metabolism, age, sex, hormones, clearance, weight, genes, medicine intake and smoking behavior, therefore the amount of caffeine required to achieve the desired effect also varies greatlyand Since that the coffee beans are the world's primary sources of dietary caffeine this study was designed to determine the percent of the caffeine in different commercial coffee brands, the isolated caffeine was identified by different qualitative methods like TLC, and FTIR.


Cite this article:
Rasha Eldalawy, Rana Hussein Kutaif, Tahany Amir Tawfeeq, Mohammed Shamil Fayyadh. Quantitative Analysis of Caffeine in different commercial kinds of coffee in Iraq. Research Journal of Pharmacy and Technology 2023; 16(7):3358-2. doi: 10.52711/0974-360X.2023.00555

Cite(Electronic):
Rasha Eldalawy, Rana Hussein Kutaif, Tahany Amir Tawfeeq, Mohammed Shamil Fayyadh. Quantitative Analysis of Caffeine in different commercial kinds of coffee in Iraq. Research Journal of Pharmacy and Technology 2023; 16(7):3358-2. doi: 10.52711/0974-360X.2023.00555   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-7-52


REFERENCES:
1.    Chowdhury SR, MalequeM, ShihanMH. Development and Validation of a Simple RP-HPLC Method for Determination of Caffeine in Pharmaceutical Dosage Forms. Asian J. Pharm. Ana. 2012 Jan-Mar;2(1):1-4.DOI:10.5958/2231-5675.2019.00039.5
2.    Shanthakumar J., Tamilselvan T., Arunagiriet.al. Role of caffeine intake in lithium treated methylphenidate induced oxidative stress in an animal model of mania. Asian J. Pharm. Res. 2013Oct. - Dec;3(4):166-171. DOI: Not Available
3.    Deepth BVP and MuthuprasannaP. Effect of Surfactant on Extraction of Caffeine from Coffee Powder. Research J. Pharmacognosy and Phytochemistry 2012; 4(5): 271-276.DOI: Not Available.
4.    SetyawanEI, SetyowatiEP, Abdul Rohman et.al. Simultaneous Determination of EpigallocatechinGallate, Catechin, and Caffeine from Green Tea Leaves (Camellia sinensis L) Extract by RP-HPLC. Research J. Pharm. and Tech 2020; 13(3):1489-1494. http://doi.org:10.5958/0974-360X.2020.00271.1
5.    PatilP A, Suhas Mane, AtulWakse, RavikumarSawant. Evaluation of tea waste for Nitrogen, Phosphorous, Potassium (NPK) as Organic Fertilizer. Asian J. Res. Pharm. Sci. 2018; 8(4):217-218. http://doi.org:10.5958/2231- 5659.2018.00036.X.
6.    RoyA. andDasB.Effects of Caffeine on Health: A Review. Research J. Pharm. and Tech. 2015 Sep; 8(9):1312-1319.http://doi.org:10.5958/0974-360X.2015.00237.1
7.    Lella R., Mathew EM andMoorkothS. Development and Validation of a LC-MS2 Method for the Simultaneous Quantification of Caffeine and Adenosine from DBS. Research J. Pharm. and Tech. 2019; 12(12): 5878-5882. http://Doi.org:10.5958/0974-360X.2019.01019.9
8.    KumarSB. Role of Caffeine in Dementia, Alzheimer’s, Parkinsonism, Bipolar Mood Disorder. Research J. Pharm. and Tech. 2015 Nov;8(11):1582-1587.http://DOI.org:10.5958/0974-360X.2015.00282.6
9.    El-Nabarawi MA, Teaima MH and Hamid et.al. Formulation, Evaluation and Antioxidant activity of Caffeine Fast Melt Tablets. Research J. Pharm. and Tech 2018;11(7):3131-3138.http://DOI.org:10.5958/0974-360X.2018.00575.9
10.    M. Muthukkaruppan, A. Nithya, P. Parthiban. Caffeine Estimation in Darjeeling District Tea Samples. Research J. Pharm. and Tech 2018; 11(5):1981-1983.http://DOI.org:10.5958/0974-360X.2018.00368.2
11.    Olechno, E., Pu´scionJakubik, A., Zujko, M.E.,Socha, K.Influence of Various Factors on Caffeine Content in Coffee Brews. Foods 2021 May; 10(6):1208. https://doi.org/10.3390/foods10061208
12.    Hamad M.N. and Abdul-Hussain D. A. Gravimetric Estimation of Caffeine in Different Commercial Kinds of Tea Found in the Iraqi Market. Iraqi J Pharm Sci. 2010 Mar; 19(2): 48-53.https://doi.org/10.31351/vol19iss2pp48-53
13.    Blakseley J., Wood D., Howse C. and Spencer-Peet J. A simplified thin-layer chromatography system for the detection of commonly abused basic drugs. Ann. Clin. Biochem. 1987 Sep; 24(5):508-510.https://doi.org/10.1177/000456328702400514
14.    El-Bagary R.I., Mohammed N.G. and Nasr H.A. Two Chromatographic Methods for the Determination of Some Antimigraine Drugs. Anal Chem Insights. 2012 May; 7: 13–21.https://doi.org/10.4137/ACI.S8864
15.    Allison RT. and Garratt NJ. Solvent systems for thin layer chromatography of biological dyes. Med. Lab. Sci. 1989 Apr; 46(2):113-9.PMID: 2593771.
16.    Fox GP., Wu A., Liang Y and Force L. Variation in caffeine concentration in single coffee beans. Journal of Agricultural and Food Chemistry 2013 Nov 13; 61(45):10772-8. http://DOI.org:10.1021/jf4011388
17.    Hongjie M., Wei X., Franklin SB. and Wu H. Geographical variation and the role of climate in leaf trait of a relic tree species across its distribution in China. Plant Biology 2017 Jul; 19(4):552-561. http://DOI.org:10.1111/plb.12564
18.    Chen X., Ma Z. and Kitts DD. Effects of processing method and age of leaves on phytochemical profiles and bioactivity of coffee leaves. Food Biochemistry 2018 May; 249:143-153.http://DOI.org:10.1016/j.foodchem.2017.12.073
19.    Bastian F. and Syarifuddin A. Effect of decaffeination and re-fermentation on level of caffeine, chlorogenic acid and total acid in green bean robusta coffee. IOP Conference series earth and environmental science 2021; 807(2):022069.https://doi.org/10.1088/1755-1315/807/2/022069
20.    Cordoba N., Pataquiva L. and Ruiz RY. Effect of grinding, extraction time and type of coffee on the physicochemical and flavour characteristics of cold brew coffee. Sci. Rep. 2019 Jun 11; 9(1):844.http://DOI.org:10.1038/s41598-019-44886-w


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