Author(s): Nagvenkar Pratiksha, Nazareth Celina

Email(s): celinanaz@yahoo.com

DOI: 10.52711/0974-360X.2023.00700   

Address: Nagvenkar Pratiksha, Nazareth Celina*
Department of Pharmaceutical Chemistry, PES’s Rajaram and Tarabai Bandekar College of Pharmacy, Farmagudi, Goa, India – 403401.
*Corresponding Author

Published In:   Volume - 16,      Issue - 9,     Year - 2023


ABSTRACT:
A Novel UV spectrophotometric method has been developed for the simultaneous estimation of ezetimibe and rosuvastatin based on Q absorption ratio method. The wavelengths of 234.8nm (lsosbestic point) and 242nm (?max of rosuvastatin) were chosen as analytical wavelengths. The linearity was established in concentration range 2-40µg/mL for ezetimibe and rosuvastatin with correlation coefficient greater than 0.990. Analytical method validation was performed by following ICH guidelines. The % assay for ezetimibe and rosuvastatin in tablet formulation complied with acceptance criteria. The developed method thus can be used as a powerful quality control tool for simultaneous analysis of the drugs in bulk and in formulation by UV spectroscopy.


Cite this article:
Nagvenkar Pratiksha, Nazareth Celina. Simultaneous Analysis of Ezetimibe and Rosuvastatin by Q absorption Ratio Method. Research Journal of Pharmacy and Technology 2023; 16(9):4276-0. doi: 10.52711/0974-360X.2023.00700

Cite(Electronic):
Nagvenkar Pratiksha, Nazareth Celina. Simultaneous Analysis of Ezetimibe and Rosuvastatin by Q absorption Ratio Method. Research Journal of Pharmacy and Technology 2023; 16(9):4276-0. doi: 10.52711/0974-360X.2023.00700   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2023-16-9-44


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