Author(s): Jyotishna Singh, Aishwarya Singhal, Abhishek Kumar Pandey, Amit, Sarita Mallik, Manish Kumar Dubey

Email(s): mkmkdubey@gmail.com

DOI: 10.52711/0974-360X.2024.00421   

Address: Jyotishna Singh1, Aishwarya Singhal1, Abhishek Kumar Pandey1, Amit1, Sarita Mallik2, Manish Kumar Dubey3*
1Department of Biosciences, School of Basic and Applied Sciences, Galgotias University, Greater Noida 203201, Uttar Pradesh, India.
2School of Biological and Life Sciences, Galgotias University, Greater Noida 203201, Uttar Pradesh, India.
3Department of Biotechnology, University Centre for Research and Development (UCRD), Chandigarh University, Mohali, Punjab 140413, India.
*Corresponding Author

Published In:   Volume - 17,      Issue - 6,     Year - 2024


ABSTRACT:
Plants are an essential source of many therapeutics and play an important role in human health. Therefore, this study was aimed toward the comparative study of two medicinally important plants, Alstonia scholaris and Tinospora cordifolia. Phytochemical screening was performed on the plants for the detection of saponin, tannin, steroids, flavonoids, alkaloids, glycosides, terpenoids, quinones, phenols, lignin, carbohydrate, protein, phalobatannins, phytosterol, oils and fats. Moreover, the plants were also analyzed for the presence of vitamins and the abundance of some other crucial phytochemicals was also estimated along with amino acids. The comparative results suggest that vitamins A and C were present in T. cordifolia whereas A. scholaris only possessed vitamin C. Total of eight amino acids were observed in A. scholaris in contrast nine were detected in T. cordifolia. The amino acid content of the plants was different, however, methionine was present in both. Kjeldahl’s method was used for the evaluation of nitrogen and protein content. A. scholaris showed higher nitrogen and protein content than T. cordifolia. Among phytochemicalcarbohydrates, saponin and tannin in K3Fe(CN)6 solution were present in greater quantity in T. cordifolia whereas A. scholaris had a higher content of phenols, alkaloids and tannin in FeCl3 solution.


Cite this article:
Jyotishna Singh, Aishwarya Singhal, Abhishek Kumar Pandey, Amit, Sarita Mallik, Manish Kumar Dubey. Phytochemical Investigation on Tinospora cordifolia and Alstonia scholaris. Research Journal of Pharmacy and Technology. 2024; 17(6):2689-3. doi: 10.52711/0974-360X.2024.00421

Cite(Electronic):
Jyotishna Singh, Aishwarya Singhal, Abhishek Kumar Pandey, Amit, Sarita Mallik, Manish Kumar Dubey. Phytochemical Investigation on Tinospora cordifolia and Alstonia scholaris. Research Journal of Pharmacy and Technology. 2024; 17(6):2689-3. doi: 10.52711/0974-360X.2024.00421   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2024-17-6-40


REFERENCES:
1.    Adiga HS, Ram HNA, Adiga RS, Jagadish PC. Evaluating the significance of the traditional use of Alstonia scholaris Linn. In Tulunadu region of South India. Research J. Pharm. and Tech. 2019; 12(8): 3878-3882.
2.    Nanditha R, Saravanan J, Praveen TK, Deepa S, Rymbai E. Evaluation of Anti-cancer, Antioxidant and Antimicrobial Activities of Alstonia scholaris L. Research J. Pharm. and Tech. 2020; 13(9): 4153-4157.
3.    Baliga MS. Alstonia scholaris Linn R Br in the treatment and prevention of cancer: past, present, and future. Integr. Cancer Ther. 2010; 9(3): 261-269. https://doi.org/10.1177/1534735410376068
4.    Kattupalli S, Vesta V, Vangara S, Uppuluri S. The multi-activity herbaceous vine –Tinospora cordifolia. Asian J. Pharm. Clin. Res. 2019; 12:1-4. https://doi.org/10.22159/ajpcr.2019.v12i3.29949.
5.    Gautam A, Kaur H, Kaur A, Prashar PK, Sood A, Singh SK, et al. Tinospora cordifolia: A Successful Story from Botanical background to Pharmaceutical Product. Research J. Pharm. and Tech. 2020; 13(11): 5620-5630.
6.    Biswasroy P, Panda S, Das C, Das D, Kar DM, Ghosh G. Tinospora cordifolia– A plant with Spectacular natural immunobooster. Research J. Pharm. and Tech. 2020; 13(2): 1035-1038.
7.    Sahu R, Mohapatra TK, Subudhi BB. Drug Interaction Potential of Tinospora cordifolia: A Review. Research J. Pharm. and Tech. 2018; 11(11): 5179-5183.
8.    Pagariya A, Jain NK. In-vivo Anti-inflammatory tеsting of еxtracts and its fractions obtained from Saptaparn lеavеs (Alstonia scholaris Linn. R. Br). Research J. Pharm. and Tech. 2020; 13(3): 1285-1288.
9.    Saha S, Ghosh S. Tinospora cordifolia: One plant, many roles. Anc. Sci. Life. 2012; 31(4): 151-159. https://doi.org/10.4103/0257-7941.107344
10.    Khyade MS, Kasote DM, Vaikos NP. Alstonia scholaris (L.) R. Br. and Alstonia macrophylla Wall. ex G. Don: A comparative review on traditional uses, phytochemistry and pharmacology. J. Ethnopharmacol. 2014; 153(1): 1-18. https://doi.org/10.1016/j.jep.2014.01.025.
11.    Ahirwal L, Singh S, Dubey MK, Bharti V, Mehta A, Shukla S. In vivo immunomodulatory effects of the methanolic leaf extract of Gymnema sylvestre in Swiss Albino mice. Arch. Biol. Sci. 2015; 67(2): 561-570.https://doi.org/10.2298/ABS141027018A
12.    Khokhani K, Ram V, Bhatt J, Khatri T, Joshi H. Spectrophotometric and Chromatographic Analysis of Amino Acids Present in Leaves of Ailanthus excelsa. Int. J. Chem. Tech. Res. 2011; 4:389-393.
13.    Magomya AM, Kubmarawa D, Ndahi JA, Yebpella GG. Determination of plant proteins via the Kjeldahl method and amino acid analysis: A comparative study. Int. J. Sci. Technol. Res. 2014; 3(4): 68-72.
14.    Koehn CJ, Sherman WC. The determination of vitamin A and carotene with the photoelectric colorimeter. J. Biol. Chem. 1940; 132: 527-538. https://doi.org/10.1016/S0021-9258(19)56200-7
15.    Haugen HN. The determination of thiamine by the thiochrome method. Scand. J. Clin. Lab. Investig. 1960;12:253-260.https://doi.org/10.3109/00365516009062434
16.    Elnenaey ES, Soliman R. A sensitive colorimetric method for estimation of ascorbic acid. Talanta. 1979; 26(12): 1164-1166. https://doi.org/10.1016/0039-9140(79)80033-8
17.    Auwal MS, Saka S, Mairiga IA, Sanda KA, Shuaibu A, Ibrahim A. Preliminary phytochemical and elemental analysis of aqueous and fractionated pod extracts of Acacia nilotica (Thorn mimosa). Vet. Res. Forum. 2014; 5(2): 95-100.
18.    Morsy, N. Phytochemical analysis of biologically active constituents of medicinal plants. Main Group Chem. 2014;13:7-21. https://doi.org/10.3233/MGC-130117
19.    Rajasree RS, Ittiyavirah SP, Naseef PP, Kuruniyan MS, Anisree GS, Elayadeth-Meethal M. An evaluation of the antioxidant activity of a methanolic extract of Cucumis melo L. fruit (F1 hybrid). Separations 2021; 8(8):123. https://doi.org/10.3390/separations8080123
20.    Singh S, Mehta A, Ahirwal L, Dubey MK, Kumar R, Mishra A, Bharti V, Sedha S. Combinational effect of Cajanus cajan, Silybum marianum and Andrographis paniculata on Invivo antioxidant and hepatoprotective activities of carbon tetrachloride intoxicated Albino rats. Annu. Rev. Res. Biol. 2014; 4(4): 665-674. https://doi.org/10.9734/ARRB/2014/6022
21.    Ahirwal L, Singh S, Dubey MK, Bharti V, Mehta A. Investigation of antioxidant potential of methanolic extract of Swertia chirata Buch. Ham. European J.Med. Plants 2014; 4(11): 1345-1355. https://doi.org/10.9734/EJMP/2014/8933
22.    Mistry D, Parekh B, Meonis, P. Studies on phytochemical constituents and antioxidant activity of Alstonia scholaris. Int. J. Life Sci. 2016;4:529-538.
23.    Sood S. Studies on the nutritional evaluation of dietetic and sugar based giloy (Tinospora cordiofolia) beverage. Int. J. Nutr. Food Sci. 2016; 1(5): 1–4. https://doi.org/10.19080/NFSIJ.2016.01.555572
24.    Shanmugapriya D, Jayanthi G. Phytochemical and antioxidant activity of methanolic leaf extract of Alstonia scholaris Linn. J. Pharmacogn. Phytochem. 2019; SP2: 466-471.
25.    Shervani ZA, Mishra PK. Phytochemical study of Tinospora cordifolia grown on three different soil conditions. Res. J. Life Sci. Bioinfo. Pharm. Chemical Sci. 2019. https://doi.org/10.26479/2019.0502.60
26.    Pandey V, Vaishya J, Balakrishnan P, Nesari T. Nutritional aspects of Tinospora cordifolia (Giloe). Med. Plants - Int. J. Phytomed. Relat. Ind. 2020; 12:158. https://doi.org/10.5958/0975-6892.2020.00021.0

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank

Journal Policies & Information


Recent Articles




Tags


Not Available