Author(s):
Nani Wijayanti DN, Lunardhi Susanto, Ana Khusnul Faizah, Maya Indrawati
Email(s):
nani.wijayanti@hangtuah.ac.id
DOI:
10.52711/0974-360X.2024.00468 
Address:
Nani Wijayanti DN*, Lunardhi Susanto, Ana Khusnul Faizah, Maya Indrawati
Department of Clinical Pharmacy, Faculty of Medicine, Universitas Hang Tuah Surabaya,
Arif Rahman Hakim Street No. 150, Surabaya, East Java, Indonesia.
*Corresponding Author
Published In:
Volume - 17,
Issue - 7,
Year - 2024
ABSTRACT:
Padina australis is a kind of brown algae seen in vast quantities in Indonesian coastal waters. Padina australis usually uses as an antibacterial, anti-tumour, fungicide, and herbicide in the pharmaceutical industry. This utilization links to the presence of primary and secondary metabolites in Padina australis. This study aimed to see if a 96% ethanol extract of Padina australis has antibacterial activity against Escherichia coli ATCC 25922. The antibacterial activity was determined using the well diffusion method. The results of phytochemical screening of the 96% ethanol extract of Padina australis showed the content of secondary metabolites such as alkaloids, flavonoids, terpenoids, steroids, tannins, saponins, and polyphenols. The results of the antibacterial activity test of 96% ethanol extract of Padina australis with a concentration of 5%, 10%, and 15% showed that there was an anti-bacterial activity against Escherichia coli ATCC with a strong category. The inhibition zone were11.64±0.13mm, 14.27±0.54mm, and 15.19±0.46mm. It indicated that the 96% ethanol extract of Padina australis contains biological metabolites which has potential activity as antibacterial. This findings still to investigate the antibacterial activity of the 96% ethanol extract of Padina australis in greater depth, additional study is needed by raising the test concentration.
Cite this article:
Nani Wijayanti DN, Lunardhi Susanto, Ana Khusnul Faizah, Maya Indrawati. Bacterial activity of Ethanol Extract 96% Padina australis against Escherichia coli ATCC 25922. Bacterial activity of Ethanol Extract 96% Padina australis against Escherichia coli ATCC 25922. Research Journal of Pharmacy and Technology.2024; 17(7):2999-3. doi: 10.52711/0974-360X.2024.00468
Cite(Electronic):
Nani Wijayanti DN, Lunardhi Susanto, Ana Khusnul Faizah, Maya Indrawati. Bacterial activity of Ethanol Extract 96% Padina australis against Escherichia coli ATCC 25922. Bacterial activity of Ethanol Extract 96% Padina australis against Escherichia coli ATCC 25922. Research Journal of Pharmacy and Technology.2024; 17(7):2999-3. doi: 10.52711/0974-360X.2024.00468 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2024-17-7-1
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