Author(s):
Shagun Malik, Amit Bhardwaj
Email(s):
malikshagun90@gmail.com , amitmds1980@rediffmail.com
DOI:
10.52711/0974-360X.2025.00771 
Address:
Shagun Malik1, Amit Bhardwaj2
1Ph.D. Scholar, Department of Periodontology, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India.
2Director, Ph.D. Cell, Professor, Department of Periodontology, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 11,
Year - 2025
ABSTRACT:
Aims & Background: To formulate an herbal Local Drug Delivery agent in the form of a gel using Achyranthes aspera root powder and to test is antimicrobial efficacy against the periodontal pathogens namely A. actinomycetemcomitans and P. gingivalis. Key words: Achyranthes aspera, Aggregatibacter actinomycetemcomitans, Anti-Microbial Activity, Local Drug Delivery, Porphyromonas gingivalis, Materials and Methods: The plant root powder is firstly used to prepare an extract to test its antimicrobial activity via MIC and MBC tests. Then, further evaluation of the antimicrobial activity of the LDD gel prepared using Achyranthes aspera root powder was done. Results: The results manifested the MIC against A. actinomycetemcomitans to be 25µl/ml and for P. gingivalis MIC to be 50µl/ml and MBC for both to be 50µl/ml. Conclusion: The antimicrobial efficiency of the preparation has been established proving it to be efficacious agains the two main periodontal pathogens. Clinical significance: The plant extract can be utilized as an herbal alternative to the commercially available antibiotics.
Cite this article:
Shagun Malik, Amit Bhardwaj. Evaluation of Anti-Microbial Activity of Achyranthes aspera Root against Periodontal Pathogens - An In Vitro Study. Research Journal Pharmacy and Technology. 2025;18(11):5353-7. doi: 10.52711/0974-360X.2025.00771
Cite(Electronic):
Shagun Malik, Amit Bhardwaj. Evaluation of Anti-Microbial Activity of Achyranthes aspera Root against Periodontal Pathogens - An In Vitro Study. Research Journal Pharmacy and Technology. 2025;18(11):5353-7. doi: 10.52711/0974-360X.2025.00771 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-11-33
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