Author(s):
Srinivasa Rao Narala, K. Saraswathi
Email(s):
srinunarala@gmail.com
DOI:
10.52711/0974-360X.2025.00846 
Address:
Srinivasa Rao Narala1*, K. Saraswathi2
1Department of Chemistry, R.V.R. and J.C. College of Engineering, Guntur, A.P., India.
2Department of Chemistry, S.V. University, Tirupathi, A.P., India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 12,
Year - 2025
ABSTRACT:
Two new visible spectrophotometric methods (A and B) for the determination of Meropenem have been proposed. These methods are based on the oxidation of the drug with Fe (III) and the estimation of Fe (II) produced after chelation with either 1,10- Phenanthroline or Potassium Ferricyanide in acidic medium at 508nm (for method A) and at 780nm (for method B). The Beer’s law was obeyed in the concentration range of 1.0-4.0 µg/ml (for method A) and 2.0-10µg/ml (for method B). Thus results of the proposed methods were validated statistically and applied successfully for the determination of Meropenem in bulk and its dosage forms.
Cite this article:
Srinivasa Rao Narala, K. Saraswathi. Utilization of Oxidation and Chelation reactions for Spectrophotometric Determination of Meropenem in Pharmaceutical Formulations. Research Journal Pharmacy and Technology. 2025;18(12):5861-3. doi: 10.52711/0974-360X.2025.00846
Cite(Electronic):
Srinivasa Rao Narala, K. Saraswathi. Utilization of Oxidation and Chelation reactions for Spectrophotometric Determination of Meropenem in Pharmaceutical Formulations. Research Journal Pharmacy and Technology. 2025;18(12):5861-3. doi: 10.52711/0974-360X.2025.00846 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-12-36
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