Author(s): Solaiman Doba, Anna Buzlama, Egor Aleksenko, Olga Sviridova

Email(s): suliman.Doba@manara.edu.sy , silversleman23@gmail.com , buzlama@pharm.vsu.ru , buzlamaa@yandex.ru

DOI: 10.52711/0974-360X.2025.00854   

Address: Solaiman Doba1, Anna Buzlama2, Egor Aleksenko2, Olga Sviridova2
1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Manara University, Syria.
2Department of Pharmacology and Clinical Pharmacology, Faculty of Pharmacy, Voronezh State University, Russia.
*Corresponding Author

Published In:   Volume - 18,      Issue - 12,     Year - 2025


ABSTRACT:
This review pays attention to literature concerning the recent pleiotropic pharmacological effects of a s-methylmethionine sulfonium chloride (MMSC), commonly referred to as vitamin U. This article highlights the important pharmacological protective effects of MMSC for various organs, including the stomach, liver, kidneys, skin, eyes and brain. It aims to reference numerous studies conducted in recent years that have utilized this substance. Despite the small amount of articles and research studies, the notable antioxidant and anti-inflammatory properties of this substance, along with its extensive range of target organs and tissues and its low toxicity, position it as a promising candidate for the development of novel medicines. This underscores the necessity for further investigation into the effects of MMSC. The most promising outcomes warranting additional investigation are antioxidant, anti-inflammatory, gastroprotective, hepatoprotective, nephroprotective, photoprotective and wound healing effects. The existing body of research is insufficient and necessitates further exploration of alternative disease models, as well as a more comprehensive examination of the characteristics of this substance in vitro and in vivo. It is essential to explore the effectiveness of MMSC in new dosage form with different doses and via alternative administration methods, alongside the conventional external application and oral administration utilized in preclinical research.


Cite this article:
Solaiman Doba, Anna Buzlama, Egor Aleksenko, Olga Sviridova. Pharmacological effects of S-methylmethionine sulfonium chloride (vitamin U). Research Journal Pharmacy and Technology. 2025;18(12):5911-6. doi: 10.52711/0974-360X.2025.00854

Cite(Electronic):
Solaiman Doba, Anna Buzlama, Egor Aleksenko, Olga Sviridova. Pharmacological effects of S-methylmethionine sulfonium chloride (vitamin U). Research Journal Pharmacy and Technology. 2025;18(12):5911-6. doi: 10.52711/0974-360X.2025.00854   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-12-44


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