Author(s):
Bagus Dwi Irianto Widodo, Yetti Hernaningsih, Hartono Kahar
Email(s):
yetti-h@fk.unair.ac.id
DOI:
10.52711/0974-360X.2025.00880 
Address:
Bagus Dwi Irianto Widodo1, Yetti Hernaningsih2,3*, Hartono Kahar2,3
1Clinical Pathology Residency Program, Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
2Department of Clinical Pathology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
3Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
*Corresponding Author
Published In:
Volume - 18,
Issue - 12,
Year - 2025
ABSTRACT:
HumaCount 5D CRP is an instrument for hematology examination that comprises hemoglobin, leukocytes, erythrocytes, hematocrit, and platelet examinations. Sysmex XN-1000 is one of the current established instruments for hematology examination. Comparison of the results between new and established instruments can be done by comparing each parameter in all result categories (low, normal, high). This study aims to analyze and compare the results of hematology examinations between the HumaCount 5D CRP and one of the current established instruments (the Sysmex XN-1000) on 5 parameters of hemoglobin, leukocytes, erythrocytes, hematocrit, and platelets. Comparative tests were conducted on 172 samples using HumaCount 5D CRP and Sysmex XN-1000. The result of each examined parameter was categorized into low, normal, and high. SPSS was used to analyze the data on the entire result, and each group of parameters using the normality test, and further was adjusted using parametric and non-parametric tests. The examination of the whole samples using the One-Way ANOVA test showed that the results were hemoglobin (p=0.818), leukocytes (p=0.325), erythrocytes (p=0.626), hematocrit (p=0.000), and platelets (p=0.394). Testing each parameter group, parametric and non-parametric tests were used to adjust the results of the normality test and the results were leukocytes (low p=0.109, normal p=0.010, high p=0.020), erythrocytes (low p=0.015, normal p=0.825), hemoglobin (low p=0.167, normal p=0.898), hematocrit (low p=0.000, normal p=0.000), and platelets (low p=0.472, normal p=0.088, high p=0.695). The overall test results showed that the HumaCount 5D CRP instrument has quite good results. The HumaCount 5D CRP is a fairly good hematology analyzer instrument and can be used for clinical services. However, it is necessary to be aware of the hematocrit result if there is a discordance with the patient's clinical condition.
Cite this article:
Bagus Dwi Irianto Widodo, Yetti Hernaningsih, Hartono Kahar. Compatibility of Complete Blood Count Values between HumaCount 5D CRP and Sysmex XN - 1000. Research Journal Pharmacy and Technology. 2025;18(12):6084-0. doi: 10.52711/0974-360X.2025.00880
Cite(Electronic):
Bagus Dwi Irianto Widodo, Yetti Hernaningsih, Hartono Kahar. Compatibility of Complete Blood Count Values between HumaCount 5D CRP and Sysmex XN - 1000. Research Journal Pharmacy and Technology. 2025;18(12):6084-0. doi: 10.52711/0974-360X.2025.00880 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-12-70
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