Author(s):
Betelhem Hailu T, Naveen Kumar A.D, Zenebe Teka M, Zenebe Hagos, Teklay Meles G, Gebgrekidan K, Salah Hamza S, Kamalakararao K, Krishna Chaithanya K, Sudhish Rai
Email(s):
krishnachaitanyawc@gmail.com
DOI:
10.52711/0974-360X.2025.00524 
Address:
Betelhem Hailu T1, Naveen Kumar A.D2, Zenebe Teka M1, Zenebe Hagos3, Teklay Meles G1, Gebgrekidan K1, Salah Hamza S4, Kamalakararao K5, Krishna Chaithanya K3,4*Sudhish Rai6
1Department of Biology, Post Graduate Applied Microbiology Program, College of Natural and Computational Sciences, Aksum University, Axum, Ethiopia.
2School of Medicine, Texila American University, Lusaka, Zambia, Central Africa.
3Department of Chemistry, College of Natural and Computational Sciences, Aksum University, Axum, Ethiopia.
4Department of Biochemistry, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Chennai, India.
4Department of Chemistry, College of Natural and Computational Sciences, Hawassa University, Hawassa, Ethiopia.
4Department of Biochemistry, University College of Science and Technology, Adikavi Nannaya University, Rajamahendravaram, Andhra Pradesh, India.
6Jagrani Devi Pharmacy College, Baradwar , Shakti , India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 8,
Year - 2025
ABSTRACT:
Euclea racemosa, belongs to family traditionally used for thr treatment of both infectious and noninfectious diseases and also reported that different bioactive compounds responsible for different pharmacological activity. The present study was to evaluate the phytochemical analysis and in vitro antioxidant activities of the crude leaf extracts of E.racemosa on the standard DPPH free radicals and total reducing power. The qualitative phytochemical findings revealed that the both ethyl acetate and ethanolic leaf extracts of E.racemosa shown the presence of secondary metabolites, including alkaloids, flavonoids, tannins and phenolic compounds, glycosides, and saponins. From the current results revealed that chloroform, ethyl acetate and ethanolic leaf extract of E. racemosa showed significant DPPH scavenging activity of 86.18%, 88.93% and 89.63% respectively at 100 µg/ml with IC50 values of 21.71 µg/ml, 24.43 µg/ml, and 23.54 µg/ml respectively. In addition the total reducing power of the tested crude leaf extracts both chloroform (0.837) and ethyl acetate (0.962) leave extracts of showed promising reducing power than other two tested extracts. There for it was concluded that the chloroform and ethyl acetate leave extract of E. racemosa had significant DPPH radical scavenging activity and total ferric reducing power.
Cite this article:
Betelhem Hailu T, Naveen Kumar A.D, Zenebe Teka M, Zenebe Hagos, Teklay Meles G, Gebgrekidan K, Salah Hamza S, Kamalakararao K, Krishna Chaithanya K, Sudhish Rai. Unveiling the Antioxidant Power: Exploring Phytochemical Composition and In vitro Antioxidant Evaluation of Leaf Extract from Euclea racemosa. Research Journal Pharmacy and Technology. 2025;18(8):3641-7. doi: 10.52711/0974-360X.2025.00524
Cite(Electronic):
Betelhem Hailu T, Naveen Kumar A.D, Zenebe Teka M, Zenebe Hagos, Teklay Meles G, Gebgrekidan K, Salah Hamza S, Kamalakararao K, Krishna Chaithanya K, Sudhish Rai. Unveiling the Antioxidant Power: Exploring Phytochemical Composition and In vitro Antioxidant Evaluation of Leaf Extract from Euclea racemosa. Research Journal Pharmacy and Technology. 2025;18(8):3641-7. doi: 10.52711/0974-360X.2025.00524 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-8-27
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