Author(s):
Amirthavarshini S, Nivetha L, Saritha E, Krishnendu V A
Email(s):
nivedha.laxman@gmail.com
DOI:
10.52711/0974-360X.2025.00590 
Address:
Amirthavarshini S, Nivetha L*, Saritha E, Krishnendu V A
Department of Biotechnology, PSG College of Arts and Science, Coimbatore - 14, Tamil Nadu, India.
*Corresponding Author
Published In:
Volume - 18,
Issue - 9,
Year - 2025
ABSTRACT:
This research investigates a sustainable synthesis of copper oxide (CuO) nanoparticles utilizing the aqueous leaf extract of Artabotrys hexapetalus as a reducing agent. A notable transition in color from green to brown during the synthesis signified the successful formation of CuO nanoparticles. FTIR proved the characteristic peaks between 408 and 700 cm?¹ indicated the presence of CuO nanoparticles. Additional peaks revealed functional groups (O-H, C=C, alkaloids, phenolics, halo compounds, and amines) essential for the nanoparticle reduction process. Zeta potential measured a negative surface charge of CuO with -1.41mV. According to SEM analysis, the biosynthesized CuO nanoparticles were found to have a primarily spherical morphology (25-30nm) with occasional voids (42 to 76nm), which suggests a porous architecture. Due to variations in the composition of their cell walls and electrostatic interactions, Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli) were susceptible to the antibacterial effects of CuO nanoparticles. The results showed that combining 1 mg/1mL of CuO nanoparticles (225µg) with 1mg/1mL of IAA (225µg) significantly accelerated root elongation (7.5cm) and lessened the negative effects of the CuO nanoparticles. When CuO nanoparticles 150µg of 1mg/1 mL and IBA 150µg of 1mg/1mL were combined, shoot growth increased to 7.8cm. This study emphasizes the feasibility of producing eco-friendly nanoparticles from natural materials.
Cite this article:
Amirthavarshini S, Nivetha L, Saritha E, Krishnendu V A. Eco-friendly CuO Nanoparticles using Artabotrys hexapetalus. Research Journal of Pharmacy and Technology. 2025;18(9):4107-1. doi: 10.52711/0974-360X.2025.00590
Cite(Electronic):
Amirthavarshini S, Nivetha L, Saritha E, Krishnendu V A. Eco-friendly CuO Nanoparticles using Artabotrys hexapetalus. Research Journal of Pharmacy and Technology. 2025;18(9):4107-1. doi: 10.52711/0974-360X.2025.00590 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2025-18-9-10
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