ABSTRACT:
There has been a surge in research on the longevity of Ayurvedic medicine in recent years. As the risks and shortcomings of modern medicine have become more evident, there is a shift in the global perspective towards the use of herbal therapy. The bulk of Ayurvedic formulations are made from herbs. Lozenges are a highly common dosage form for cold and cough drugs because they make patient compliance easier. The goal of this research is to create a polyherbal lozenge and assess how the alterations in accelerated stability testing affected the physicochemical parameters. The final lozenges' quality was assessed using the following criteria: pH, density, and total solid content. Three batches with sugar bases of 40%, 50%, and 60% w/v were created. The following physicochemical parameters were assessed for each batch: total solid content, pH, specific gravity, color, flavor, and smell. For example, solid content (37–56.75%), pH (4.8–5.0), and specific gravity (1.24–1.36). The prepared batches were subjected to microbial testing and stability investigations; during the course of the three-month investigation, no turbidity or microbial growth was detected. Every batch guarantees reproducibility, and every parameter complied with requirements.