Author(s): Cholpon Kamchibekova, Kaiyrkul Shalpykov

Email(s): kamchibekova@mymail.academy

DOI: 10.52711/0974-360X.2026.00017   

Address: Cholpon Kamchibekova1, Kaiyrkul Shalpykov2*
1Department of Fundamental Disciplines, The International School of Medicine (ISM) of the International University of Kyrgyzstan (IUK), Bishkek, Kyrgyzstan.
2Institute of Chemistry and Phytotechnology NAS KR, National Academy of Sciences Kyrgyz Republic, Bishkek, Kyrgyzstan.
*Corresponding Author

Published In:   Volume - 19,      Issue - 1,     Year - 2026


ABSTRACT:
In order to expand the range of medicines for the treatment of diseases musculoskeletal system, peripheral nervous system and muscle-tonic disorders in the Institute of Chemistry and Phytotechnology of the National Academy of Sciences of Kyrgyz Republic has developed a balsamic ointment a local irritating effect, which contains a complex physiologically active substances of medicinal plant flora growing in the sharply continental climate of Kyrgyzstan. It has an analgesic, anti-inflammatory, revulsive and warming effect, reflexively corrects nonspecific resistance and stimulates the body's defenses. In this work we carried out physicochemical, analytical and pharmacological studies. Considering the prevalence of the above diseases of musculoskeletal system, peripheral nervous system, muscular-tonic disorders, injuries after intense training in athletes and for the fastest normalization of body function, we have proposed a medicinal ointment of natural origin.


Cite this article:
Cholpon Kamchibekova, Kaiyrkul Shalpykov. Development of a medicinal ointment of natural origin. Research Journal of Pharmacy and Technology. 2026;19(1):113-8. doi: 10.52711/0974-360X.2026.00017

Cite(Electronic):
Cholpon Kamchibekova, Kaiyrkul Shalpykov. Development of a medicinal ointment of natural origin. Research Journal of Pharmacy and Technology. 2026;19(1):113-8. doi: 10.52711/0974-360X.2026.00017   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-1-17


REFERENCES:
1.    Sudhakar S, Paul J, Selvam SP, Mahendranath P. Influence of aminotransferase enzyme on delayed onset muscle soreness among novice athletes: A pilot single-blind randomized clinical trial. Res J Pharm Technol. 2019; 12(9): 4373–8. doi: 10.5958/0974-360X.2019.00752.2.
2.    Jeon M, Oh H, Lim H, Yun HJ. Development of reference point of doping attitude and dispositions for anti-doping education notification of athletes: Application of reference group model. Iran J Public Health. 2024; 53(2): 348–55.
3.    Soltani N, Fatahi A. Flatfoot deformity; exercise to therapeutic interventions: A systematic review. Iran J Public Health. 2024; 53(2): 305–12.
4.    Ramezanghorbani N, Hajiabedin Rangraz M. Sports medicine: Scientometric of 10 years of global scientific productions. Iran J Public Health. 2023; 52(9): 1984–94.
5.    Atkinson AJ. Principles of Clinical Pharmacology. Moscow: Practical Medicine. 2013.
6.    Kuznetsova OY. Review of modern drugs with biologically active compositions of the birch chaga mushroom. Development and Registration of Medicines. 2016; 1: 128–41.
7.    Kuzmina IV. Optimization of reflex methods of influence for dorsopathies: Abstract of thesis. Moscow; 2015. 22 p.
8.    Mashkovsky MD. Medicines. Chisinau: Cartea Moldovenaske; 1989. Part 1–2. p. 30–332, 146–338.
9.    Modern methods of treating diseases of the musculoskeletal system [Internet]. Direct line of the newspaper "7 days". Available from: http://www.belta.by. Accessed 2021 Dec 2.
10.    Ergasheva MS, Ergashev Kh. Medicinal plants of Uzbekistan used for the treatment and prevention of diseases of the musculoskeletal system. Act Sci Res Mod World. 2017; 4–6: 113–5.
11.    Atrooz OM, Al-Awaida M, Al-Ameer HJ, Uysal H. Evaluating the antioxidant capacity, phenolic contents, and anticancer potential of Caralluma europaea extracts. Adv Life Sci. 2024; 11(4): 862–70. doi: http://dx.doi.org/10.62940/als.v11i4.3296.
12.    Gupta V, Tyagi S, Jain P, Tripathi R. Evaluation of the bioactive compounds and its functional role in the aquatic weed Pistia stratiotes. Res J Pharm Technol. 2024; 17(1): 87–5. doi: 10.52711/0974-360X.2024.00014.
13.    Korzhevsky DE. Molecular Neuromorphology. Special Lit, Saint Petersburg. 2015; 110 p.
14.    Lisunkin YI, Mohort NA. Pharmacological effects on sensory nerve endings. Health, Kiyv. 1991; p. 18–105.
15.    Onyekwelu I, Goldring MB, Hidaka C. Chondrogenesis, joint formation, and articular cartilage regeneration. J Cell Biochem. 2009; 107(3): 383–92.
16.    Roy T, Chakraborty P, Roy Chowdhury R, Chatterjee TK. Possible beneficial role of novel anti-osteoarthritic drug diacerein in rheumatoid arthritis. Res J Pharm Technol. 2022; 15(6): 2715–0. doi: 10.52711/0974-360X.2022.00454.
17.    Irawan C, Solihat I, Praptiwi SS, Mufidah M, Listianti E, Safitri B. Effect of extraction method on antioxidant activity, anti-inflammation, and cytotoxicity of Curcuma aeruginosa Roxb. rhizome. Res J Pharm Technol. 2024; 17(5): 2180–4. doi: 10.52711/0974-360X.2024.00343.
18.    Altymyshev AA, Zotov EP, Orozov MA, Kamchibekova C,Toktonalieva NZ, Yusuphanov Musahan Y. date RF No. 1794454. Balsamic ointment Karagay. State Committee for Inventions, Moscow. 1992.
19.    Olariu L, Vacaru A, Pyatigorskaya N, Vacant AM. Original Romanian product involved in cellular chondromodulatory mechanisms. Euroinvent medalia de aur. Catalog Euroinvent. 2016; 437.
20.    Tallheden T, Bengtsson C, Brantsing C, Sjogren-Jansson E. Proliferation and differentiation potential of chondrocytes from osteoarthritic patients. Arthritis Res Ther. 2005; 7: 560.
21.    Goldring MB, Otero M, Plumb DA, Dragomir C. Roles of inflammatory and anabolic cytokines in cartilage metabolism. Eur Cells Mater. 2011; 21: 202–20.
22.    Guilak F, Fermor B, Keefe FJ, Kraus VB. The role of biomechanics and inflammation in cartilage injury and repair. Clin Orthop Relat Res. 2004; 423: 17–26.
23.    Muravyov IA. Technology of dosage forms. Medicine, Moscow. 1988; p. 203–12.
24.    FS 42-2456-86. Petrolatum.
25.    GOST 23683-89, grade P-1. Solid petroleum paraffin.
26.    State Pharmacopoeia of the USSR. Medicine, Moscow. 1968,1987; ed. 10-11. 
27.    FS 42-2520-88. Lanolin anhydrous.
28.    FS 42-916-74. Menthol.
29.    Voronchikhin SI, Timonov PS. Turpentine in medicine. Clinical aspects of traumatology and orthopedics; 1981. Vol. 2. p. 264–6.
30.    Saibel OL, Dargaeva TD, Zaiko LN. Development of a method for quantitative determination of the amount of polyphenol compounds in the underground organs of the marsh cinquefoil. Bulletin of the Buryat State University. 2008; 12: 17–21.
31.    Ministry of Health of Russia. Temporary Methodological Guidelines Prevention, Diagnosis, and Treatment of Novel Coronavirus Infection (COVID-19). Version 18 (26.10.2023) [together with Recommendations for Describing Chest Radiography and CT Data, Instructions for Diagnosing COVID-19 Using Nucleic Acid Amplification Methods, Instructions for Diagnosing COVID-19 Using Immunochemical Methods, "Recommended Outpatient Treatment Regimens, Recommended Inpatient Treatment Regimens, Instructions on Infection Safety Measures for Emergency Medical Teams]. Ministry of Health of Russia; 2023.
32.    Guide to Preclinical Drug Research. Part 1. Grif and K, Moscow. 2012; 944 p.
33.    Chirkina NN, Patudin AB. Antimicrobial properties of essential oils and aromatic resins of species of the genus cultivated in the Crimea. Biol Sciences. 1971; 11: 100–3.
34.    Javed S, Bibi A, Shoaib A, Perveen S, Ferdosi MFH. Essential oil of Eucalyptus citriodora: Physio-chemical analysis, formulation with hand sanitizer gel and antibacterial activity. Adv Life Sci. 2022; 9(4): 510–5.
35.    Jabeen S, Suma BV. Simultaneous determination of Cefepime and Tazobactam by using Hyphenated Liquid Chromatography (UPLC-MS/MS). Res J Pharm Technol. 2024; 17(1): 67–3. doi: 10.52711/0974-360X.2024.00011.
36.    Seema BR, Jyothi Y, Bhovi CN, Aradhya MVV, Lekhak M, Mane SR. Advanced up and down methodology for acute toxicity assessment with reliable LD50 verified by aqueous extract of curly kale using wistar rats. Res J Pharm Technol. 2023; 16(10): 4519–4. doi: 10.52711/0974-360X.2023.00736.
37.    Kyere CG, Boateng M, Osei SA, Frimpong YO, Poku PA, Korankye O, Twumasi GK, Owusu AK. Effect of photoperiod on semen production and thermo-physiological responses of the Pearl Guinea fowl in hot humid environment. Int J Agric Biosci. 2024; 13(4): 603–9.
38.    Ivanov MA, Kosovich NL, Malevskaya SS, Nagrodsky IA, Eliashberg MG. Turpentines substances of wood and cellulose. Moscow. 1968. p. 1–182.
39.    Cherukuri S, Paramanayagam A, Prabakaran R, Mayakannan M, Vuppalapati L. Evaluation of cutaneous wound healing activity of Citrus aurantium fruit peel extract-based ointment in albino rats. Res J Pharm Technol. 2023; 16(1): 250–4. doi: 10.52711/0974-360X.2023.00046.
40.    Eskandari SE, Samadi A, Kardeh S, Dowlati Y, Yazdi HA, Firooz A. Photobiomodulation therapy for improvement of body contour: A retrospective study on Middle Eastern participants. Iran J Public Health. 2024; 53(8): 1858–63.
41.    Khademi A, Mansuri P, Pahlevan D, Bozorgi M, Nasiri M, Hejazi S, Azizian Z, Shirbeigi L. Efficacy of pumpkin ointment in treatment of chronic hand eczema: A randomized, active-controlled, double-blind clinical trial. Iran J Public Health. 2020; 49(7): 1339–47.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.52711/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank

Journal Policies & Information


Recent Articles




Tags


Not Available