Author(s):
Maria J Anggakusuma, Chiquita Prahasanti, Westy Agrawanty, Mohammed Ahmed Aljunaid, Michael G Wijaya, Huda Rashad Qaid
Email(s):
chiquita-p-s@fkg.unair.ac.id
DOI:
10.52711/0974-360X.2026.00037 
Address:
Maria J Anggakusuma1, Chiquita Prahasanti2*, Westy Agrawanty1, Mohammed Ahmed Aljunaid3,4, Michael G Wijaya1, Huda Rashad Qaid4
1Residence in Periodontic Program, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
2Department of Periodontology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
3Department of Oral and Dental Medicine, Faculty of Medicine, Taiz University, Taiz, Yemen.
4Faculty of Oral and Dental Medicine, Al-Saeed University, Taiz, Yemen.
*Corresponding Author
Published In:
Volume - 19,
Issue - 1,
Year - 2026
ABSTRACT:
Background/aim: Bone graft materials are commonly used to promote successful periodontal tissue treatments. However, these materials have various drawbacks while being widely utilized. A recent study focuses on tooth grafts to address the flaw. This study compared osteocalcin expression in bone healing following incisor extraction socket grafting with tooth graft and xenograft hydroxyapatite. Materials and methods: The study conducted experiments on thirty-three adult male Cavia cobaya randomly divided into hydroxyapatite tooth graft, hydroxyapatite xenograft, and control group (no treatment). Bone tissue sections were stained with hematoxylin-eosin and diaminobenzidine to analyze osteocalcin expression through immunohistochemical evaluation. Results: The Kruskal-Wallis test was used to compare each group, with a significance level of p=0.05. The results revealed a significant difference in mean osteocalcin between groups (p < 0.05). Osteocalcin expression was higher in the tooth graft group and lowered in the control group. Conclusion: The findings indicate that tooth grafts hold great potential as a new material for bone grafting, given their osteoinductive and osteoconductive properties, which are comparable to those of xenografts.
Cite this article:
Maria J Anggakusuma, Chiquita Prahasanti, Westy Agrawanty, Mohammed Ahmed Aljunaid, Michael G Wijaya, Huda Rashad Qaid. Tooth Materials-hydroxyapatite Compound: A New Invention in Bone Grafting Material. Research Journal of Pharmacy and Technology. 2026;19(1):263-8. doi: 10.52711/0974-360X.2026.00037
Cite(Electronic):
Maria J Anggakusuma, Chiquita Prahasanti, Westy Agrawanty, Mohammed Ahmed Aljunaid, Michael G Wijaya, Huda Rashad Qaid. Tooth Materials-hydroxyapatite Compound: A New Invention in Bone Grafting Material. Research Journal of Pharmacy and Technology. 2026;19(1):263-8. doi: 10.52711/0974-360X.2026.00037 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-1-37
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