Author(s):
Madhav B. Korde, Suparna S. Bakhle, Vaibhav P. Uplanchiwar, Vinod M. Thakare, Anshu R. Dudhe
Email(s):
madhavkorde07@gmail.com
DOI:
10.52711/0974-360X.2026.00063 
Address:
Madhav B. Korde*1, Suparna S. Bakhle2, Vaibhav P. Uplanchiwar1, Vinod M. Thakare1, Anshu R. Dudhe1
1Nagpur College of Pharmacy, Wanadongri, Hingna Road, Nagpur - 441110 (M.S.)
2Priyadarshini J.L. College of Pharmacy, Electronic Zone Building, MIDC, Hingna Road, Nagpur - 440016 (M.S.)
*Corresponding Author
Published In:
Volume - 19,
Issue - 1,
Year - 2026
ABSTRACT:
Topical gel preparations are designed for application on the skin or mucosal surfaces to deliver medications effectively, bypassing first-pass metabolism and enhancing localized therapeutic effects, particularly in pain management and the treatment of skin conditions. Nonsteroidal anti-inflammatory drugs (NSAIDs), known for their potent anti-inflammatory and analgesic properties, are increasingly favored for topical administration to mitigate the adverse effects often associated with their oral counterparts. In this context, hydrophilic polymers such as Carbopol 940 have been employed to develop topical hydrogel formulations containing diclofenac sodium. The objective of the study was to formulate and assess various topical dosage forms containing diclofenac sodium, methyl nicotinate, and methyl salicylate, and to evaluate their therapeutic efficacy in managing both acute and chronic pain. Six batches of a gel formulation combining methyl nicotinate, diclofenac sodium, and methyl salicylate were developed and tested.
Cite this article:
Madhav B. Korde, Suparna S. Bakhle, Vaibhav P. Uplanchiwar, Vinod M. Thakare, Anshu R. Dudhe. Design, Characterization and Evaluation of Topical Analgesic gel for Acute and Chronic pain. Research Journal of Pharmacy and Technology. 2026;19(1):432-8. doi: 10.52711/0974-360X.2026.00063
Cite(Electronic):
Madhav B. Korde, Suparna S. Bakhle, Vaibhav P. Uplanchiwar, Vinod M. Thakare, Anshu R. Dudhe. Design, Characterization and Evaluation of Topical Analgesic gel for Acute and Chronic pain. Research Journal of Pharmacy and Technology. 2026;19(1):432-8. doi: 10.52711/0974-360X.2026.00063 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-1-63
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