Author(s):
P.C. Jeba Preethi Jansi, Jeni Chandar Padua
Email(s):
pc.jebapreethi@gmail.com
DOI:
10.52711/0974-360X.2026.00185 
Address:
P.C. Jeba Preethi Jansi1*, Jeni Chandar Padua2
1Department of Zoology, Holy Cross College (Autonomous), Nagercoil, Tamilnadu, India.
2Affiliated to Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, India.
*Corresponding Author
Published In:
Volume - 19,
Issue - 3,
Year - 2026
ABSTRACT:
The purpose of the study was to examine the antioxidant, and anti-inflammatory activity of aqueous extract of Anisomeles malabarica leaves. Antioxidant activity was assessed using DPPH, Nitric oxide, and superoxide scavenging assays and in vitro anti-inflammatory activity was evaluated using Protein denaturation assay i.e. egg albumin and bovine serum albumin. The antioxidant and anti-inflammatory properties of an aqueous extract of A. malabarica leaves were evaluated in vitro. Preliminary phytochemical screening indicated the presence of alkaloids, flavonoids, phenols, tannins, quinones, polysaccharides, saponins and absence of anthroquinones. The IC50 values for each assay were calculated using standard graphs. Remarkable free radicals scavenging ability with concentration dependent inhibition was observed in all the tested radicals with IC50 namely, DPPH (49.68 µg/ml), nitric oxide (NO) (61.11µg/ml) and superoxide (44.39 µg/ml). The inhibition rate of egg albumin and bovine serum albumin protein denaturation increased gradually with increasing concentrations from 100-500 µg/ml. Anti-inflammatory assay recorded IC50 of egg albumin (372.40 µg/ml), bovine serum albumin (355.86 µg/ml). The results suggest the potential use of Anisomeles malabarica as an excellent antioxidant with strong anti-inflammatory impact discovery builds the enough scientific frameworks in future to isolate and purify the bioactive components for further uses.
Cite this article:
P.C. Jeba Preethi Jansi, Jeni Chandar Padua. Evaluation of In Vitro Antioxidant and Anti-Inflammatory activities of Anisomeles malabarica Leaf Extract. Research Journal Pharmacy and Technology. 2026;19(3):1295-0. doi: 10.52711/0974-360X.2026.00185
Cite(Electronic):
P.C. Jeba Preethi Jansi, Jeni Chandar Padua. Evaluation of In Vitro Antioxidant and Anti-Inflammatory activities of Anisomeles malabarica Leaf Extract. Research Journal Pharmacy and Technology. 2026;19(3):1295-0. doi: 10.52711/0974-360X.2026.00185 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2026-19-3-46
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