Preparation, Numerical Optimization and Evaluation of Ciprofloxacin PLGA and PLA Nanoparticles by Solvent Displacement Technique

S Rajarajan; R Chandramouli

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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Preparation, Numerical Optimization and Evaluation of Ciprofloxacin PLGA and PLA Nanoparticles by Solvent Displacement Technique

Author(s): S Rajarajan, R Chandramouli

Email(s): pharmking@gmail.com

DOI: Not Available

Address: S Rajarajan1* and R Chandramouli2
1Karnataka College of Pharmacy, Bangalore 560 064, Karnataka
2CARISM, Sastra University, Thanjavur - 613 402. Tamil Nadu, India.
*Corresponding Author

Published In: Volume - 2, Issue - 1, Year - 2009

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ABSTRACT:
The aim of the current study to prepare and characterization of drug as a nanoparticles by numerical optimization method by using ciprofloxacin as a model drug and using Ploy (Lactic –co- glycolic acid) PLGA and (Poly lactic acid) PLA. The particles were prepared by solvent displacement technique. The formulations were evaluated in terms of surface character, Particle size, drug loading efficacy and separation of free drug. The mean diameter was dependent on Polymer concentration.

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Cite this article:
S Rajarajan, R Chandramouli. Preparation, Numerical Optimization and Evaluation of Ciprofloxacin PLGA and PLA Nanoparticles by Solvent Displacement Technique. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 186-190.

Cite(Electronic):
S Rajarajan, R Chandramouli. Preparation, Numerical Optimization and Evaluation of Ciprofloxacin PLGA and PLA Nanoparticles by Solvent Displacement Technique. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 186-190. Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2009-2-1-91