ABSTRACT:
Plant medicines are traditionally used for the treatment of some renal diseases and also have been reported to show significant diuretic activity. In the present study powder of Hemidusmus indicus root was extracted with distilled water to get aqueous extract. During development of syrup, several combinations of sucrose, sorbitol, glycerin, methyl paraben, propyl paraben and distilled water were tried. The formulation was checked for its stability and consistency. Depending upon the results of evaluation, the formula had been finalized for liquid syrup preparation. Among different compositions, good consistency was obtained using sucrose, sorbitol, glycerin, methyl paraben, propyl paraben in the ratio 30:10:2.2:0.07:0.03. Also, better acceptability was obtained by incorporation of mint flavor (0.2%). The specific gravity of syrup was found to be 1.06068 g/ml. The refractive index and viscosity was found to be 1.339 and 2.4216cp.The pH was found to be 5.62 .The single drug preparation can be used for diuretic activity for elderly patients since oral route for single drug preparation is one of the simplest and claimed to be safest.