ABSTRACT:
The solubility of a drug is one of the most important part of the drug formulation development. The effectiveness of drug is completely depends on the, solubility and bioavailability. This article reviews the various preparation techniques for solid dispersion and compiles some of the recent technology transfers. The different types of solid dispersions based on the molecular arrangement have been highlighted. Some of the practical aspects to be considered for the preparation of solid dispersions, such as selection of carrier and methods of physicochemical characterization, alongwith an insight into the molecular arrangement of drugs in solid dispersions are also discussed.
Cite this article:
Nikam Shreya Pradeep. A Review: Increasing Solubility of Poorly Soluble Drugs, by Solid Dispersion Technique. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1933-1940.
Cite(Electronic):
Nikam Shreya Pradeep. A Review: Increasing Solubility of Poorly Soluble Drugs, by Solid Dispersion Technique. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1933-1940. Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2011-4-12-21