Exploring the Protective Role of Water Extract of Spirulina platensis on Flutamide-Induced Lipid Peroxidation Using 4-Hydroxy Nonenal and Nitric Oxide as Model Markers

Supratim Ray

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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Exploring the Protective Role of Water Extract of Spirulina platensis on Flutamide-Induced Lipid Peroxidation Using 4-Hydroxy Nonenal and Nitric Oxide as Model Markers

Author(s): Supratim Ray

Email(s): supratimray_in@yahoo.co.in

DOI: Not Available

Address: Supratim Ray*
Division of Pharmaceutical Chemistry, Dr. B C Roy College of Pharmacy and Allied Health Sciences, Bidhannagar, Durgapur, 713 206, India
Corresponding author

Published In: Volume - 4, Issue - 12, Year - 2011

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ABSTRACT:
This in vitro study was designed with an aim to evaluate free radical scavenging activity of water extract of Spirulina platensis on flutamide-induced lipid peroxidation using 4-hydroxy nonenal and nitric oxide as model markers. In this study goat liver has been used as liver source. The results suggest that flutamide could induce lipid peroxidation to a significant extent and it was also found that water extract of the Spirulina platensis has the ability to suppress the flutamide-induced toxicity.

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Cite this article:
Supratim Ray. Exploring the Protective Role of Water Extract of Spirulina platensis on Flutamide-Induced Lipid Peroxidation Using 4-Hydroxy Nonenal and Nitric Oxide as Model Markers. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1857-1860.

Cite(Electronic):
Supratim Ray. Exploring the Protective Role of Water Extract of Spirulina platensis on Flutamide-Induced Lipid Peroxidation Using 4-Hydroxy Nonenal and Nitric Oxide as Model Markers. Research J. Pharm. and Tech. 4(12): Dec. 2011; Page 1857-1860. Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2011-4-12-4