ABSTRACT:
Wound a clinical entity is as old as mankind, often possesses problems in clinical practice. Naturally the investigative curiosity to promote the healing continues since ages. A lot of research has been envisaged to develop the better healing agents and it has been a challenging task to generate them and keep up the pace with problems encountered. Several drugs of plant, mineral, and animal origin are described in the Ayurveda for their wound healing properties. Most of these drugs are derived from plant origin. Some of these plants have been screened scientifically for the evaluation of their wound healing activity in different pharmacological models. Some Ayurvedic medicinal plants namely, Argemone mexicana, Boerhaavia diffusa, Catharanthus roseas, Diospyros cardifolia, Eclipta alba, Ficus religiosa, Hypericum perforatum, Lawsonia inermis, Merremia tridentate, and Swertia chirata, were found to be effective in experimental models. The rapidity of wound healing depends to a considerable extent on the contraction that begins a few days after injury and continues for a several weeks. In the present review attempts are made to understand various aspects of wound healing in terms of percentage closure of wound, period of complete epithelialization, tensile strength, histopathology, weight of granuloma in different wound models.