Author(s): Ranjith Anishetty1, 2*, Satya Swapna1, B. Aishwarya1, K. Chaitanya Sravanthi1

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Address: 1Vignan Institute of Pharmaceutical Sciences, Deshmukhi Village, Nalgonda-508 824,Andhra Pradesh, India. 2Department of Quality Assurance, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara - 144402, Punjab, India

Published In:   Volume - 5,      Issue - 10,     Year - 2012

Pharmaceutical industries have produced a number of new antibiotics in the last decades, resistance to these drugs by micro organisms has also increased. For a long period of time, plants have been a valuable source of natural products for maintaining human health, especially in the last decade, with more intensive studies for natural therapies. The use of plant extracts and phytochemicals both with known antimicrobial properties can be of great significance in therapeutic treatments. The main objective is to study the anti microbial activity of the combined plant extracts which was evaluated with antibiotic susceptible and resistant microorganisms. The possible synergistic effects were studied. Extracts from the following plants were utilized: Ricinus communis (castor), Zingiber officinalis (ginger) and Punica granatum (pomegranate). The highest antimicrobial potential were observed for the extracts of pomegranate and castor and comparative studies were made in order to know the activity of combined extracts of Ginger and pomegranate, pomegranate and castor, Ginger and castor and also pomegranate, ginger and castor and the results showed synergistic antibacterial activity against antibiotic resistant bacteria.

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RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

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