Author(s):
El harti Jaouad1*, Ansar M’hammed1, Lmimouni Badr2, Benomar Ali3, Taoufik Jamal1
Email(s):
Email ID Not Available
DOI:
Not Available
Address:
1Laboratory of Medicinal Chemistry, Faculty of Medicine and Pharmacy, BP 6203, Rabat Institute, University Mohammed V Souissi, Rabat, Morocco.
2Laboratory of Parasitology-Mycology, Instruction Military Hospital Mohammed V, Rabat, Morocco.
3Research Cent
Published In:
Volume - 5,
Issue - 10,
Year - 2012
ABSTRACT:
The treatment of hydatidosis is primarily surgical but can cause morbidity or mortality, hence the interest in many cases of medical treatment whose main representative is albendazole. The efficacy of this compound against Echinococcus granulosus cysts is proved, but limited by its poor bioavailability. New potential prodrugs were synthesized and their protoscolicidal activity was tested in vitro. Although hydrogen N°1 is important for the albendazole activity, some derivatives have kept an activity relatively important.
Cite this article:
Not Available
Cite(Electronic):
Not Available Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2012-5-10-30