N. S. Devshetwar1, L.V.G. Nargund1*, Nirmal T. Havannavar2, Shachindra L. Nargund3
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1Department of Pharmaceutical Chemistry, Nargund College of Pharmacy, Dattatreya Nagar, II main,100Ft ring Road, BSK II stage, Bangalore- 560085 (India).
2Professor and Head, Dept. of Pharmaceutical Chemistry, MMU College of Pharmacy, Ramanagar.
Volume - 5,
Issue - 10,
Year - 2012
Indole containing organic compounds forms a significant class of drugs which exhibit an array of biological activities ranging from antibacterial, antifungal, anti-inflammatory, antipyretic to CNS depressants and anticancer. The present work aimed to synthesize novel 1-(6-Chloro-5-fluoro-3-phenyl-1H-indol-2-yl)-ethanone derivative with a desire to obtain potent antibacterial activity. The synthesized derivatives are characterized by Melting point, TLC, IR and 1H NMR spectra and then compounds are screened in-vitro antibacterial activity.
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