ABSTRACT:
The Drakshadi gutika is effective for amlapitta, hrddahakanthadaha, trsna, murccha, agnimandaya and amavata is official in Ayurveduc formulary in India. Quantification of active principles through modern analytical tools is essential for establishing the authenticity, creditability, prescription and usage of Ayurvedic medicines/herbal formulations. The Ayurvedic formulation Drakshadi gutika has been prepared as per Ayurvedic formulary of India was estimated spectrophotometrically for its tannic acid content. Three-laboratory batch of Drakshadi gutika were estimated for their tannic acid contents against standard tannic acid solution on double beam UV-Visible Spectrophotometer at Lambda max 276 nm. The concentration of tannic acid present in raw material was found to be 8.057± 0.29w/w in Terminalia belerica, and 1.283%±0.64 w/w in vitis vinifera and in three identical laboratory batch of Drakshadi gutika DG-I, DG-II and DG-III, was found to be 3.132±0.396, 3.124±0.396, 3.119±0.682w/w respectively. The tannic acid content of all the three batches is found to be in close proximities with each other and recovery studies are indicative of reproducibility of method. Hence the present method is simple, sensitive, precise and accurate and can be adopted for routine quality control of Drakshadi gutika.