ABSTRACT:
A clinically relevant drug-drug interaction (DDI) occurs when the effectiveness or toxicity of one medication is altered by the administration of another medicine or a substance that is administered for medical purposes (to be distinguished from drug-food interactions). Adverse consequences of DDIs may result from either diminished therapeutic effect or toxicity. Among the various types of medical errors, the occurrence of adverse DDIs is one that is usually preventable. It is therefore essential that health professionals be able to evaluate the potential for DDIs and, when detected, to determine appropriate prevention or management strategies. In this study a patient drugs profile with multiple complicacies were evaluated for drug-drug interaction presence. Some drug-drug interactions were found moderate to severe level among the drugs taken by patient. Clopidogrel/Atorvastatin and Clopidogrel /proton-pump inhibitor interaction were the noticeable found- which should be taken in to consideration seriously when such drugs are prescribed concurrently by the health professionals.