ABSTRACT:
The total numbers of patients screened were 50 which 86% were males and 14% females. The types of cases were diabetes mellitus (1%) post operative wounds (16%) and non surgical wounds(88%), wound in patients with prolonged hospital stay constituted 14%. The pathogen isolated were Gram positive 24(39%), Gram negative 27(43%). The Gram positive organism isolated were Staphylococcus aureus 12%, Methicillin resistant Staphylococcus aureus(6%), Staphylococcus (5%) and Enterococcus Feacalis (3%).Gram negative organisms isolated were Pseudomonas (16%), Escherichia coli(10%) Acintobactor (11%), Proteus species(5%) and Enterobactor (1%), No growth were (17%), moreover (66%) of gram positive organism and (57%) of gram negative organism showed resistance to more than 3 antibiotics proves a chance become a multidrug resistant organism and cause disease. In randomized of, controlled trials, Linezolid 600 mg twice daily provided effective antimicrobial therapy for gram positive soft tissue infection including MRSA.Skin and soft tissue infections one common types of infection that may contribute the longer hospital stays, significantly increase the cost of medical care and one likely to have an important role in the development of antimicrobial resistance Staphylococcus aureus has been found to be the most frequently isolated pathogen causing skin and soft tissue infection.