ABSTRACT:
Recurrent aphthous stomatitis (recurrent aphthae) is a disease of man characterized by painful, recurrent, single or multiple necrotizing ulcerations of mucosal tissues. It is prevalent in 25% of the population. This disorder generally begins during adolescence, increases into adulthood, and then decreases with advancing age.RAS has been divided into two forms, minor aphthous ulcersand major aphthous ulcers. Most patients are otherwise healthy. Although self-limited in nature, some individuals experience frequent and severe episodes, so that RAS may be associated with significant morbidity. The underlying etiology remains unclear, and no curative treatment is available.However, multiple therapeutic regimens exist that may provide significant symptomatic relief to the individuals with frequently recurrent or severe disease.Recurrence may be precipitated by trauma, hormonal changes in women, physical or psychic stress, and chemical irritants.The present review examines the existing treatments for RAS with the purpose Of treating the patients in a clinical scenario.this involves topical and systemic therapy of administrating drugs like antibiotics, ant-inflammatory drugs, anaesthetics and corticosteroids.Currently,it is recognized asan immunologically mediated, inflammatory oral conditionrather than an infectious disease.