Author(s): Jahanzeb Khan, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman

Email(s): zaib_zaib94@yahoo.com

DOI: Not Available

Address: Jahanzeb Khan*, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman
Department of Pharmacy, The University of Lahore, Lahore, Pakistan.
*Corresponding Author

Published In:   Volume - 7,      Issue - 2,     Year - 2014


ABSTRACT:
Antihyperglycemic, hypoglycemic and cytotoxic activities of methanolic extract of Albizia lebbeck and Trigonella corniculata were studied. Hypoglycemic action of plants was investigated using normoglycemic rabbits (acute study only), whereas antihyperglycemic activity was studied using alloxan induced diabetic rabbits (acute and chronic study). Results revealed both plant extracts and their mixture having significant anti diabetic potential at dose of 200mg/kg comparable to standard drug Glibenclamide (0.5 mg/kg). Brine shrimp assay was used for the determination of cytotoxicity and results showed plants to have low toxic potential (LD50>1000 microgram). The study conducted proves both plants and their mixture to have high potential for the treatment of diabetes.


Cite this article:
Jahanzeb Khan, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman. Antihyperglycemic, Hypoglycemic and Cytotoxic Activity of Albizia lebbek and Trigonella corniculata. Research J. Pharm. and Tech. 7(2): Feb. 2014; Page 191-195.

Cite(Electronic):
Jahanzeb Khan, Muhammad Asad Saeed, Saad Touqeer, Sharjeel Adnan, Zeeshan Masood, Muhammad Zaman. Antihyperglycemic, Hypoglycemic and Cytotoxic Activity of Albizia lebbek and Trigonella corniculata. Research J. Pharm. and Tech. 7(2): Feb. 2014; Page 191-195.   Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2014-7-2-6


Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags


Not Available