ABSTRACT:
Herbal medicine has become an item of global importance both medicinal and economical. Although usage of these herbal medicines has increased, their quality, safety and efficiency are serious concerns in industrialized and developing countries. Plant play a vital role in curing various ailments of the man and herbal remedies are getting increasing patient compliance as they are devoid of typical side effects of allopathic medicines. The present research has been undertaken with the aim to formulate and evaluate the herbal gel containing Hibicus syriacus leaf extract. The gel formulation was designed by using methanolic extract in varied concentrations and was evaluated using physiochemical parameter. The gel was prepared by using Carbopol 934, Propylene glycol, Methanol, Hibiscus syriacus, and required amount of distilled water. Then skin pH (6.8-7) was maintained by drop wise addition of tri-ethanolamine. The physiochemical parameters of formulations (pH, viscosity, spreadability etc.) were determined. Stability studies were carried out as per ICH guidelines for 3 months at different temperatures and humidity. The results showed that formulation F5 containing 2.5% Sesbania grandiflora extract have better stability than other formulation.