ABSTRACT:
The objective of this investigation was to predict the toxic properties of Sodium tellurite against selected human pathogens. A group of six human bacterial pathogens Staphylococcus aureus, Strepto pyogenes, Bacillus subtilis, Proteus vulgaris, Escherichia coli and Klebsiella planticola were utilized for screening. The spectrum of toxic properties was compared by means formation of zone. Our study demonstrated that sodium tellurite exhibit a strong toxic effect on B. subtilis (30±2mm), P. vulgaris (27 ± 2 mm) and S. aureus (25 ± 0.5 mm). The activity was compared with standard Ciprofloxacin disc (5µg/disc) and the zone of inhibition was 24 ± 1.4 mm. However, Gram negative bacteria exhibited resistance to Sodium tellurite except proteus vulgaris that we screened in our study. Our study suggested that the anti bacterial effect of sodium tellurite is not wider spectrum but selectively more significant even when compared with standard Ciprofloxacin.