A novel methodology for the synthesis of teriflunomide using hydrotropes as a reaction media

Yashwant S. Surve; Dharmesh G. Panchal; R.S Lokhande

doi:10.5958/0974-360X.2015.00226.7

Research Journal of Pharmacy and Technology

ISSN

0974-360X (Online)
0974-3618 (Print)

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A novel methodology for the synthesis of teriflunomide using hydrotropes as a reaction media

Author(s): Yashwant S. Surve, Dharmesh G. Panchal, R.S Lokhande

Email(s): yashwantsurveresearch@gmail.com

DOI: 10.5958/0974-360X.2015.00226.7

Address: Yashwant S. Surve*, Dharmesh G. Panchal, and R.S Lokhande
School of Basic science, Department of Chemistry. Jaipur National University, Jaipur
*Corresponding Author

Published In: Volume - 8, Issue - 9, Year - 2015

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ABSTRACT:
This paper describes the synthesis of teriflunomide (Active pharmaceutical ingredients), used in the treatment of multiple sclerosis. The synthesis of teriflunomide was carried out using three different hydrotropes. The effect of these hydrotropes on yield, quality of product was studied at two different temperature conditions.

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Cite this article:
Yashwant S. Surve, Dharmesh G. Panchal, R.S Lokhande. A novel methodology for the synthesis of teriflunomide using hydrotropes as a reaction media. Research J. Pharm. and Tech. 8(9): Sept, 2015; Page 1247-1249. doi: 10.5958/0974-360X.2015.00226.7

Cite(Electronic):
Yashwant S. Surve, Dharmesh G. Panchal, R.S Lokhande. A novel methodology for the synthesis of teriflunomide using hydrotropes as a reaction media. Research J. Pharm. and Tech. 8(9): Sept, 2015; Page 1247-1249. doi: 10.5958/0974-360X.2015.00226.7 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2015-8-9-2