Author(s):
Sandra Sagar, Gopinath P
Email(s):
Email ID Not Available
DOI:
10.5958/0974-360X.2016.00315.2 
Address:
Sandra Sagar1, Dr.Gopinath P2
1BDS 2nd Year, Saveetha Dental College, Saveetha University, Chennai
2Senior Lecturer, Department Of Microbiology, Saveetha Dental College, Saveetha University, Chennai
Corresponding Author
Published In:
Volume - 9,
Issue - 10,
Year - 2016
ABSTRACT:
Widespread spread of CTX-M type extended-spectrum beta-lactamases (ESBL) in E. coli strains which are resistant to extended-spectrum cephalosporins is the most remarkable example for rapid and global spread of plasmid mediated antimicrobial resistance in bacteria. The incessant spread and global prevalence of ESBL resistance poses a serious threat to the human health, as it is responsible for the narrowing of therapeutic options pertaining to infections. A sum of 20 uropathogenic isolates of E. coli were subjected for the antibiotic susceptibility pattern using different antibiotics and followed by the detection of bla CTX-M gene by PCR. By which, we found increased percentage of isolates were resistant to different antibiotics and 30% of them were having this gene. This indicates the prevalence of such antibiotic resistance gene in our region. Proper antibiotic policies would promote the patients health condition better.
Cite this article:
Sandra Sagar, Gopinath P. Detection of bla CTX-M gene for ESBL Production Among Clinical Isolates of Escherichia coli. Research J. Pharm. and Tech 2016; 9(10):1593-1595. doi: 10.5958/0974-360X.2016.00315.2
Cite(Electronic):
Sandra Sagar, Gopinath P. Detection of bla CTX-M gene for ESBL Production Among Clinical Isolates of Escherichia coli. Research J. Pharm. and Tech 2016; 9(10):1593-1595. doi: 10.5958/0974-360X.2016.00315.2 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2016-9-10-14