Author(s):
Ashna A, Jeena S, Vidhya PV, Venkateswaramurthy. N, Sambathkumar. R
Email(s):
venkateswaramurthy.n@jkkn.org
DOI:
10.5958/0974-360X.2016.00187.6 
Address:
Ashna A, Jeena S, Vidhya PV, Venkateswaramurthy. N*, Sambathkumar. R
J.K.K. Nattraja College of Pharmacy, Kumarapalyam, Tamil Nadu, India
*Corresponding Author
Published In:
Volume - 9,
Issue - 7,
Year - 2016
ABSTRACT:
Statins are most effective in reducing the plasma cholesterol level by inhibiting hydroxyl methyl glutaryl coenzyme A reductase. Emerging evidence suggest that statins exert other mechanism of action called Pleiotropic effects; which are plaque stability, endothelial function modification, thrombus formation etc. Therefore therapeutic potential of statins extends beyond lipid lowering. Correctly underlying these pleiotropic effect suggest a new method to prevent and treat wide variety of life threatening disorders. Thus statins has added a wide scope of potential targets ranging from acute coronary syndrome to other renal infections and neuroleptic disorders.
Cite this article:
Ashna A, Jeena S, Vidhya PV, Venkateswaramurthy. N, Sambathkumar. R. Statins: Pleiotropic Effect. Research J. Pharm. and Tech. 2016; 9(7):977-981. doi: 10.5958/0974-360X.2016.00187.6
Cite(Electronic):
Ashna A, Jeena S, Vidhya PV, Venkateswaramurthy. N, Sambathkumar. R. Statins: Pleiotropic Effect. Research J. Pharm. and Tech. 2016; 9(7):977-981. doi: 10.5958/0974-360X.2016.00187.6 Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2016-9-7-48