Author(s):
Sisira Padavala, Gopinath P
Email(s):
Email ID Not Available
DOI:
10.5958/0974-360X.2016.00281.X 
Address:
Sisira Padavala1, Dr. Gopinath P2
1BDS 2nd year, Saveetha Dental College, Saveetha University, Chennai.
2 Senior Lecturer, Department of Microbiology, Saveetha Dental College, Saveetha University, Chennai.
*Corresponding Author
Published In:
Volume - 9,
Issue - 9,
Year - 2016
ABSTRACT:
Capsular polysaccharides (K antigens) are one of the main virulence factors for Escherichia coli strains to cause urinary tract infections and neonatal meningitis. There are 50 chemically different capsular K antigens found, wherein only a few are associated with infective E.coli strains. These polysaccharides associated with disease that encodeK1 antigen (polysialic acid) are involved in causing a wide variety of infections such as septicemia, urinary tract infections, and meningitis. A total of 20 clinical isolates of E. coli were screened for the presence of neuC gene by PCR. We have observed 15% positivity among our isolates. This indicates that, the pathogenicity of urinary tract infections by these pathogens might be crucially played by this gene encoding K capsular polysaccharide.
Cite this article:
Sisira Padavala, Gopinath P. Detection of neuC gene for the presence of capsular polysaccharide among the clinical isolates of Escherichia coli. Research J. Pharm. and Tech 2016; 9(9):1454-1456. doi: 10.5958/0974-360X.2016.00281.X
Cite(Electronic):
Sisira Padavala, Gopinath P. Detection of neuC gene for the presence of capsular polysaccharide among the clinical isolates of Escherichia coli. Research J. Pharm. and Tech 2016; 9(9):1454-1456. doi: 10.5958/0974-360X.2016.00281.X Available on: https://www.rjptonline.org/AbstractView.aspx?PID=2016-9-9-33