ABSTRACT:
Objective: the present study was conducted to validate in-vitro anthelmintic activity of various extract hexane, ethyl acetate, ethanol, water of eclipta prostrata (l)., aganist pheritima posthuma by petri-dish method. Method: the in-vitro trial for anthelmintic activity of various extract of eclipta prostrata(l)., was conducted on mature live pheritima posthuma by petri-dish method. The extracts were used at the concentration of 5mg, 10mg, and 15mg and observation were made on their viability at room temperature. Results: among the various extract, only ethyl acetate and ethanol have anthelmintic activity. 5mg, 10mg, 15 mg/ml of ethyl acetate have produced paralytic effect at 34minutes minutes, 29 minutes and 20 minutes and mortality was confirmed at 111 minutes, 61 minutes and 46 minutes.5mg, 10mg, 15 mg/ml of ethanol have produced paralytic effect at 27 minutes, 23 minutes and 17 minutes and mortality was confirmed at 83 minutes, 72 minutes and 34 minutes respectively. Conclusion: an anthelmintic has been confirmed as the various extract shows good anthelmintic activity against pheritima posthuma. In the present investigation, the whole plant of eclipta prostrata (l)., was taken up for extensive studies “ preliminary phytochemical and pharmacological studies of the whole plant of eclipta prostrata (l)., (asteraceae).