ABSTRACT:
Fast dissolving tablet are the novel dosage form which is well accepted now a days by geriatric and pediatric patients because it does not need water to swallow. The aim of the present article is to study the natural polymers and the formulation approach of mouth dissolving tablets. MDTs are solid dosage forms containing medicinal substances which disintegrate rapidly, usually in a matter of seconds, when placed on the mouth. New MDT technologies address many pharmaceutical and patient needs ranging from enhanced life-cycle management to convenient dosing for pediatric, geriatric, and psychiatric patients with dysphagia. This has encouraged both academia and industry to generate new orally disintegrating formulations and technological approaches in this field. The aim of this article is to review the development of MDTs, challenges in formulation, new MDT technologies, evaluation methodologies, suitability of drug candidates, and future prospects.